Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2009-08-20
2010-12-07
Rawlings, Stephen L (Department: 1643)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S007100, C536S023500, C536S024310, C536S024330, C530S350000, C530S387100, C530S387700, C436S064000
Reexamination Certificate
active
07846667
ABSTRACT:
The present invention provides methods for aiding in the diagnoses of the neoplastic condition of a lung cell and methods of screening for a potential therapeutic agent for the reversal of the neoplastic condition.
REFERENCES:
patent: 3817837 (1974-06-01), Rubenstein et al.
patent: 3850752 (1974-11-01), Schuurs et al.
patent: 3939350 (1976-02-01), Kronick et al.
patent: 3996345 (1976-12-01), Ullman et al.
patent: 4275149 (1981-06-01), Litman et al.
patent: 4277437 (1981-07-01), Maggio
patent: 4366241 (1982-12-01), Tom et al.
patent: 4603102 (1986-07-01), Himmelmann et al.
patent: 5405783 (1995-04-01), Pirrung et al.
patent: 5412087 (1995-05-01), McGall et al.
patent: 5445934 (1995-08-01), Fodor et al.
patent: 5464764 (1995-11-01), Capecchi et al.
patent: 5487992 (1996-01-01), Capecchi et al.
patent: 5578444 (1996-11-01), Edwards et al.
patent: 5578832 (1996-11-01), Trulson et al.
patent: 5627059 (1997-05-01), Capecchi et al.
patent: 5631153 (1997-05-01), Capecchi et al.
patent: 5631734 (1997-05-01), Stern et al.
patent: 5695937 (1997-12-01), Kinzler et al.
patent: 5695980 (1997-12-01), Wei et al.
patent: 5734039 (1998-03-01), Calabretta et al.
patent: 5888796 (1999-03-01), Chang
patent: 2004/0166527 (2004-08-01), Beaudry et al.
patent: 2007/0054274 (2007-03-01), Giordano
patent: 2178022 (1996-12-01), None
patent: 0717 113 (1996-06-01), None
patent: H2-53486 (1990-02-01), None
patent: WO 94/07538 (1994-04-01), None
patent: WO 95/20681 (1995-08-01), None
patent: WO 97/10365 (1997-03-01), None
patent: WO 99/50278 (1999-10-01), None
Amatschek et al. (Cancer Res. Feb. 1, 2004; 64: 844-856).
Lyon et al. (Crit. Rev. Oncog. 1994; 5 (4): 373-388).
Borges et al. (1997) “Anachaete-scutehomologue essential for neuroendocrine differentiation in the lung,”Nature386:852-855.
Chen et al. (1994) “The second intron of the K-rasgene contains regulatory elements associated with mouse lung tumor susceptibility,”Proc. Natl. Acad. Sci. USA91:1589-1593.
Chiang et al. (1991) “Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms,”J. Biol. Chem.266:18162-18171.
Chisaka et al. (1992) “Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox GeneHox-1.6,” Nature355:516-520.
Day & Thompson (1987) “Molecular cloning of cDNA coding for human PGP 9.5 protein,”FEBS Letters210(2):157-160.
Dhillon et al. (1985) “Neural markers in carcinoma of the lung,”Br. J. Cancer51:645-652.
Dorin et al. (1992) “Cystic fibrosis in the mouse by targeted insertional mutagenesis,”Nature359:211-215.
Ermisch et al. (1995) “Protein gene product (PGP) 9.5 in diagnostic (neuro-) oncology. An immunomorphological study,”Clin. Neuropath.14(3):130-136.
Gadzar et al. (1996) “NCI Series of Cell Lines: A Historical Perspective,”J. Cell Biochem. Suppl.24:1-11.
Gilbert et al. (1997) “Low specificity of PGP9.5 expression for detection of micrometastatic neuroblastoma,”Brit. J. Cancer75(12):1779-1781.
Golay et al. (1991) “Expression of C-myb and B-myb, but not A-myb, correlates with the proliferation in human hematopoietic cells,”Blood77(1):149-158.
Golay et al. (1996) “Expression of A-myb, but not c-myb and B-myb, is Restricted to Burkitt's Lymphoma, slg+ B-Acute Lymphoblastic Leukemia, and a Subset of Chronic Lymphocytic Leukemias,”Blood87(5):1900-1911.
Golay et al. (1997) “Redundant Functions of B-Myb and c-Myb in Differentiating Myeloid Cells,”Cell Growth&Differentiation8:1305-1316.
Gupta et al. (1995) “Regulation of an eukaryotic initiation factor-2 (eIF-2) associated with 67 kDa Glycoprotein (p67) and its requirement in protein synthesis,”Gene Expression5(2):113-122.
Hibi et al. (1991) “Serial Analysis of Gene Expression in Non-Small cell Lung Cancer,”Cancer Research58:5690-5694.
Hibi et al. (1999) “Frequent overexpression of PGP9.5 in a non-small cell lung cancer,”Proceedings of the American Association of Cancer Research40:610.
Hojo et al. (1998) “Overexpression of p53 protein in interstitial lung disease,”Respiratory Medicine92:184-190.
Kasai et al. (1992) “Pulmonary Large Cell Carcinoma Expressing Neuroendocrine Markers: the Morphological, Biological, and Neuroendocrine Features of Their Cell Lines and Surgical Cases,”Jpn. J. Cancer Res.83:1002-1010.
Kroegel et al. (1996) “Expression von Proto-Onkogenen, Tumor-Suppressor-Genen und dominanten Onkogenen bei Malignomen der Lunge,”Atemw.-Lungenkrkh2:133-142.
Madden et al. (1997) “SAGE transcript profiles for p53-dependent growth regulation,”Oncogene15:1079-1085.
Mooi et al. (1988) “Non-small cell lung carcinomas with neuroendocrine features. A light microscopic, immunohistochemical and ultrastructural study of 11 cases,”Histopathology13:329-337.
Nomura et al. (1988) “Isolation of human cDNA clones ofmyb-related genes, A-myband B-myb,” Nucleic Acids Research16(23):11075-11089.
Phelps et al. (1996) “NCI-Navy medical oncology branch cell line data base,”J. Cell Biochem. Suppl.24:32-91.
Rosenwald (1996) “Upregulated expression of the genes coding translation initiation factors elF-4E and elF-2α in transformed cells,”Cancer Letters102:113-123.
Salgia et al. (1998) “Molecular Abnormalities in Lung Cancer,”J. of Clinical Oncology16(3):1207-1217.
Satterwhite et al. (1994) “Inhibition of Cell Growth by TGFβ1 is Associated with Inhibition of B-mybandCyclin Ain both BALB/MK and Mv1Lu Cells,”Cell Growth&Differentiation5:789-799.
Stein (1999) “Keeping the biotechnology of antisense in context,”Nature Biotech.17(3):209.
Velculescu et al. (1995) “Serial analysis of gene expression,”Science270:484-487.
Venter et al. (1996) “A new strategy for genome sequencing,”Nature381:364-366.
Wani et al. (1998) “Enhanced expression of the 8oxo-7,8-dihydrodeoxyguanosine triphosphatasegene in human breast tumor cells,”Cancer Letters125:123-130.
Wilkinson et al. (1989) “The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase,”Science246:670-673.
Wu & Wu (1987) “Receptor-mediated in vitro gene transformation by a soluble DNA carrier system,”J. Biol. Chem.262:4429-4432.
Beaudry Gary A.
Bertlesen Arthur H.
Jen Jin
Madden Stephen L.
Sidransky David
Foley & Lardner LLP
Genzyme Corporation
Johns Hopkins University
Konski Antoinette F.
Rawlings Stephen L
LandOfFree
Methods for the diagnosis and treatment of lung cancer does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods for the diagnosis and treatment of lung cancer, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for the diagnosis and treatment of lung cancer will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4215175