Methods for the activation of proliferation of animal cells

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

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435358, 435375, C12N 506, C12N 510

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058112995

ABSTRACT:
Cell cultures are described which proliferate in a serum- and protein-free environment and which are characterized by the circumstance that the concentration of at least one cell-cycle-regulatory protein is increased during at least one period of the cell-cycle. Methods for the production of such cell cultures are presented. With these methods cell lines can be transferred to serum- and protein-free growth that are already in use in a production process which, prior to the use of these methods, requires serum or proteins added to the basal medium.

REFERENCES:
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