Methods for synthetic unrandomization of oligomer fragments

Details Methods for synthetic unrandomization of oligomer fragments Methods for synthetic unrandomization of oligomer fragments

1994-12-16

1997-12-16

Chambers, Jasemine C.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

435 6, C12Q 168, C12Q 170

Patent

active

056983913

ABSTRACT:
Methods useful for the determination of oligomers which have specific activity for a target molecule from a pool of primarily randomly assembled oligomers are provided. The disclosed methods involve repeated syntheses of increasingly simplified sets of oligomers coupled with selection procedures for determining oligomers having the highest activity. Freedom from the use of enzymes allows the application of these methods to any molecules which can be oligomerized in a controlled fashion.

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