Methods for synthesis of oligonucleotides

Details Methods for synthesis of oligonucleotides Methods for synthesis of oligonucleotides

2007-09-25

2007-09-25

Lewis, Patrick (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S025300, C536S024300

Reexamination Certificate

active

09032972

ABSTRACT:
Improved methods for synthesis of oligonucleotides and other phosphorus-linked oligomers are disclosed. The methods include the use of aromatic solvents, alkyl aromatic solvents, halogenated aromatic solvents, halogenated alkyl aromatic solvents, or aromatic ether solvents to achieve deprotection of protected hydroxyl groups.

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