Methods for separating a tocol from a tocol-containing mixture

Distillation: processes – separatory – With disparate physical separation – Utilizing liquid-liquid extracting of distillation product

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203 74, 549413, B01D 1100, B01D 300, C07D31104

Patent

active

061593478

ABSTRACT:
The invention relates to method for separating tocol from a tocol-containing admixture by heating the tocol-containing admixture composed a tocol, a fatty acid, and an esterifying compound to esterify the fatty acid to produce a second tocol admixture composed of the tocol, the esterified fatty acid, and the unesterified fatty acid; distilling the tocol-containing admixture with the esterified fatty acid to remove the unesterified fatty acid from the tocol admixture to produce a tocol admixture composed of the tocol with substantially removed unesterified fatty acid; distilling the tocol admixture for a sufficient time and temperature to substantially remove the tocol from the tocol admixture to produce a tocol admixture composed of the removed tocol and a non-tocol component; and extracting the tocol from the tocol admixture with an extraction solvent composed of a polar, organic solvent that is miscible with water to produce a two phase system composed of a first phase containing the majority of the extraction solvent and the second phase, wherein the selectivity of the extraction solvent for tocol with respect to the non-tocol component is greater than unity, and removing the first phase from the second phase, with the proviso that the extraction solvent is not a neat alcohol.

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