Methods for screening compounds that affect IL-1 epsilon...

Details Methods for screening compounds that affect IL-1 epsilon... Methods for screening compounds that affect IL-1 epsilon...

2005-01-04

2005-01-04

Andres, Janet (Department: 1647)

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

C435S007100, C435S007210, C435S069100, C435S071100, C435S320100, C435S471000, C530S350000, C436S504000

Reexamination Certificate

active

06838290

ABSTRACT:
The invention is directed to purified and isolated novel human IL-1 epsilon polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, the use of such polypeptides in cellular and immune reactions, the use of such polypeptides in screening for agonists or antagonists of IL-1 epsilon activity, and kits comprising such polypeptides.

REFERENCES:
patent: 5449758 (1995-09-01), Hartley
patent: 6197551 (2001-03-01), Busfield
patent: 0 855 404 (1998-07-01), None
patent: WO 9847921 (1998-10-01), None
patent: WO 9937662 (1999-07-01), None
Database EMBL, Entry MMA30324, Accession No. AA030324, Jan. 21, 1997, 2125184, Marra et al.
Dinarello, C.A., “Interleukin-1,”Cytokine and Growth Factor Review vol. 8(4): 253-265, 1997.

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