Methods for screening class B beta-lactamase enzymes from Bacter

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 32, 435117, 435231, 4352523, C12Q 168, C12Q 118, C12P 1700, C12N 986

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057053405

ABSTRACT:
This invention is directed to the elucidation of DNA sequences encoding Class B beta-lactamase enzymes from Bacteroides fragilis and the amino acid sequences of those enzymes. This invention is also directed to screening methods for identifying antibiotics which are resistant to such beta-lactamase enzymes or for identifying compounds which inactivate such beta-lactamase enzymes.

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