Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or... – Recovery or purification
Patent
1990-04-23
1995-01-03
Russel, Jeffrey E.
Chemistry: molecular biology and microbiology
Virus or bacteriophage, except for viral vector or...
Recovery or purification
43524021, 435243, 4352541, 435261, 436541, 436824, 436828, C12N 102, C12N 508, C12N 702
Patent
active
053786246
ABSTRACT:
A method is provided for removing a second ligand from a particle surface without substantially affecting the particle surface, comprising the step of exposing the particle to a first ligand immobilized onto a support, wherein the particle is exposed under conditions and for a residence time sufficient to allow the second ligand to desorb from the particle surface, and wherein the first ligand has an affinity for the second ligand that is at least two orders of magnitude greater than the affinity of the second ligand for the particle surface, such that the second ligand is removed from the particle surface without substantially affecting the particle surface.
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Berenson Ronald J.
Peterson Dale R.
CellPro Incorporated
Russel Jeffrey E.
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