Methods for reducing adsorption in an assay

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435962, 436527, 436531, 436544, 436546, 436815, 436825, G01N 33552, G01N 33545

Patent

active

060602600

ABSTRACT:
The present invention relates to methods for substantially reducing adsorption of at least one positively charged molecule to a negatively charged surface upon contact therebetween, the method comprising combining the positively charged molecule with at least one blocking agent in an amount sufficient to substantially reduce the adsorption of the positively charged molecule to the negatively charged surface.

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M.J. Levy and A.P. Jaklitsch (1993) "Homogenous Enzyme Immunoassays: EMIT.COPYRGT." in Diagnostics in the Year 2000 Antibody, Biosensor, and Nucleic Acid Technologies, (Singh, P. et al. Eds.) Van Nostrand Reinhold, New York and references cited therein.
Syva Co. revised Jun. 1995 product data describing cassette instructions for use with EMIT.COPYRGT. gentamicin assay.

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