Methods for reduced renal uptake of antibody fragments

Details Methods for reduced renal uptake of antibody fragments Methods for reduced renal uptake of antibody fragments

1995-03-21

1998-12-01

Huff, Sheela

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530300, 530350, 530324, C07K 500

Patent

active

058438947

ABSTRACT:
Kidney uptake of antibody fragment conjugates in patients is reduced by administration to the patient of one or more compounds selected from the group consisting of D-lysine, poly-D-lysine, or poly-L-lysine, or pharmaceutically acceptable salts or carboxyl derivatives thereof.

REFERENCES:
patent: 4701521 (1987-10-01), Ryser et al.
patent: 5380513 (1995-01-01), Gray et al.
Russo et al 1993 Amer. J. Pathology vol. 142 Nol : 261-271.
Batsford et al 1991 Clin. Exp. Immunol. vol. 86: 471-477.
The Webster's II New Riverside Dictionary, Riverside Publishing Company, pp. 72, 1003 and 1269, 1984.
Mogenson et al., Scand. J. Clin. Lab. Invest., 37: 477 (1977).
Hammond et al., Brit. J. Cancer, 67: 1437 (1993).
Pimm et al., Eur. J. Nucl. Med., 21: 663 (1994).

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