Methods for protein screening

Details Methods for protein screening Methods for protein screening

2005-08-09

2005-08-09

Celsa, Bennett (Department: 1639)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S007100, C435S007320

Reexamination Certificate

active

06927025

ABSTRACT:
This invention provides methods of protein/polypeptide screening based on the provision of libraries of individual proteins/polypeptides, which in turn can be screened for a number of activities, including cell binding and biological activity. Methods for recovering genes encoding such proteins/polypeptides are also provided.

REFERENCES:
patent: 5824485 (1998-10-01), Thompson et al.
patent: 5952171 (1999-09-01), McCarthy et al.
patent: 5955269 (1999-09-01), Ghai et al.
patent: 196 46 372 (1997-06-01), None
patent: 0174753 (1986-03-01), None
patent: WO 91 05058 (1991-04-01), None
patent: WO 92 02536 (1992-02-01), None
patent: WO 92 18645 (1992-10-01), None
patent: WO 93 03172 (1993-02-01), None
patent: WO 95 11922 (1995-05-01), None
patent: WO 95/11922 (1995-05-01), None
patent: WO 95 34648 (1995-12-01), None
patent: WO 98 48008 (1998-10-01), None
Johnstone, A.; Thorpe, R. Immunochemistry in Practice. Blackwell Scientific Publications, Oxford, England, 1987.
Knappik A., et al., An Improved Affinity Tag Based on the Flag® Reptide for the Detection and Purification of Recombinant Antibody Fragments, BioTechniques, vol. 17, (1994) pp. 754-761.
Durrant, L.G., et al., Screening of Monoclonal Antibodies Recognizing Oncofetal Antifgens for Isolation of Trophoblasts from Maternal Blood for Prenatal Diagnosis, Prenatal Diagnosis, vol. 14, (1994) pp. 131-140.
Tavitian, B., et al., In vivo imaging of oligonucleotides with positron emission tomography, Nature Medicine, vol. 4, (1998) pp. 467-471.
Maskos, U ., et al., Parallel analysis of oligodeoxyribonucleotide (oligonucleotide) interactions.I. Analysis of factors influencing oligonucleotide duplex formation, Nucleic Acids Research, vol. 20, (1992) pp. 1675-1678.
Romisch, K., et al., Homology of 54K protein of signal-recognition particle, docking protein and twoE. coliproteins with putative GTP-binding domains, Nature, vol. 340, (1989) pp. 478-482.
Tang, P ., et al., A High Affinity Digoxin-binding Protein Displayed on M13 is Functionally Identical to the Native Protein, Journal of Biological Chemistry, vol. 270, (1995) pp. 7829-7835.
Denzin, L.K., et al., Construction, Characterization, and Mutagenesis of an Anti-fluorescein Single Chain Antibody Idiotype Family, Journal of Biological Chemistry, vol. 267, (1992) pp. 8925-8931.
Mallender, W ., et al., Comparative Properties of the Single Chain Antibody and Fv Derivatives of mAB 4-4-20, Journal of Biological Chemistry, vol. 271 (1996) pp. 5338-5346.
Kraft, R., et al., Using Mini-Prep Plasmid DNA for Sequencing Double Stranded Templates with Sequenase™, BioTechniques, vol. 6, (1988) pp. 544-547.
Naryshkin, N.A., et al. Chemical Cross-Linking of the Human Immunodeficiency Virus Type 1 Tat Protein to Synthetic Models of the RNA Recognition Sequence TAR Containing Site-Specific Trisubstituted Pyrophosphate Analogues, Biochemistry, vol. 36 (1997) pp. 3496-3505.
Langer, P ., et al., Enzymatic synthesis of biotin-labeled polynucleotides: Novel nucleic and acid affinity probes, Proc. Natl. Acad. Sci., vol. 78) (1981) pp. 6633-6637.
Modjtahedi, H., et al., The human EGF receptor as a target for cancer therapy: six new rat mAbs against the receptor on the breast carcinoma MDA-MB 468, J. Cancer, vol. 67 (1993) pp. 247-253.
White, R., et al., The TATA-binding protein: a central role in transcription by RNA polymerasses I, II and III, Trends Genet, vol. 8, (1992) pp. 284-288.
Vincent, JP ., et al., Trypsin-Pancreatic Trypsin Inhibitor Association. Dynamics of the Interaction and Role of Disulfide Bridges, Biochemistry, vol. 11, (1972) pp. 2967-2977.
Phizicky, Eric, et al. Protein-Protein Interactions: Methods for Detection and Analysis, Microbiology Reviews, vol. 59, (1995) pp. 94-123.
Cash, Phillip, Protein mutations revealed by two-dimensional electrophoresis, Chromatography, vol. 698, (1995) pp. 203-224.
Hager D., et al., Elution of Proteins from Sodium Dodecyl Sulfate-Polyacrylamide Gels, Removal of Sodium Dodecyl Sulfate, and Renaturation of Enzymatic Activity: Results with Sigma Subunit ofEscherichia coliRNA Polymerase, Wheat Germ DNA Topoisomerase, and Other Enzymes, Anal. Biochemistry, vol. 109, (1980) pp. 76-86.
Chen, HZ, et al., Prokaryotic Coupled Transcription-Translation, Methods in Enzymology, vol. 101, (1983) pp. 674-690.
Dingwall Colin, et al., Human immunodeficiency virus 1 tat protein binds trans-activation-responsive region (TAR) RNA in vitro, Proc. Natl., Acad. Sci., vol. 86, (1989) pp. 6925-6929.
Chan, Edward K.L., et al., The Small Nuclear Ribonucleoprotein SS-B/La Binds RNA with a Conserved Protease-Resistant Domain of 28 Kilodaltons, Molecular and Cellular Biology, vol. 7, (1987) pp. 2588-2591.
Siegel, et al., Elongation Arrest is Not a Prerequisite for Secretory Protein Translocation across the Microsomal Membrane, Cell Biology, vol. 100, (1985) pp. 1913-1921.
Cao, J., et al., Inhibition of Nascent-Peptide Release at Translation Termination, Molecular and Cellular Biology, vol. 16, (1996) pp. 7109-7114.
Langer, P ., et al., Enzymatic synthesis of biotin-labeled polynucleotides: Novel nucleic and acid affinity probes, Proc. Natl. Acad. Sci., vol. 78) (1981) pp. 6633-6637.
Marchuck, D., et al., Construction of T-vectors, a rapid and general system for direct cloning of unmodified PCR products, Nucleic Acids Research, vol. 19, pp. 1154.
Patton, W.F., et al., Development of a Dedicated Two-Dimensional Gel Electrophoresis System that Provides Optimal Pattern Reproducibility and Polypeptide Resolution, BioTechniques, vol. 8, (1990) pp. 518-527.
Madani, N.D., et al., Candida albicans estrogen-binding protein gene encodes an oxidoreductase that is inhibited by estradiol, Proc. Natl. Acad. Sci, vol. 91 (1994) pp. 922-926.
Rosenberg, A.H., et al., Vectors for selective expression of cloned DNAs by T7 RNA polymerase, Gene, vol. 56, (1987) pp. 125-135.
Molloy, P . et al., Separation and concentration of bacteria with immobilized antibody fragments, Journal of Applied Bacteriology, vol. 78 (1995) pp. 359-365.
Pawson, T. Protein modules and signalling networks, Nature vol., 373, (1995) pp. 573-580.
Prelich, G. et al., Functional identity of proliferating cell nuclear antigen and a DNA polymerase-δ auxiliary protein, Nature, vol. 326 (1997) pp. 517-520.
Porpaczy, Z., et al., Association between the α-ketoglutarate dehydrogene comples and succinate thiokinase, Biochim, Biophys.Acta., 749, (1983) pp. 172-179.
Weber, J. et al., Combined application of site-directed Mutagenesis, 2-Azido-ATP Labeling, and Lin-Benzo-ATP, Binding to Study the Noncatalytic Sites ofEscherichia coliF1-ATPase, J. Biol. Chem., vol. 268, (1993) pp. 6241-6247.
Mattheakis, L., et al., An in vitro polysome display system for identifying ligands from very large peptide libraries, Proc. Natl. Acad. Sci., vol. 91, (1994) pp. 9022-9026.
Hanes, J., et al., In vitro selection and evolution of functional proteins by sing ribosome display, Proc. Natl. Acad. Sci., vol. 94, (1997) pp. 4937-4942.
Hutchens, T ., et al., New Desorption Strategies for the Mass Spectrometric Analysis of Macromolecules, Rapid Comms. Mass Spec., vol. 7, (1993) pp. 576-580.
Jung, S., et al., Improving in vivo folding and stability of a single-chain-Fv antibody fragment by loop grafting, Protein Engineering, vol. 10, (1997) pp. 959-966.

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