Methods for protecting allogeneic islet transplant using...

Details Methods for protecting allogeneic islet transplant using... Methods for protecting allogeneic islet transplant using...

2007-12-04

2007-12-04

Gambel, Phillip (Department: 1644)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C424S134100, C530S350000, C530S387300

Reexamination Certificate

active

10155514

ABSTRACT:
The present invention is a method of inhibiting islet cell transplant rejection, particularly to treat diabetes, such as type-1 and type-2 diabetes, by administering to a subject an effective amount of a soluble CTLA4 mutant molecule. One example of a soluble CTLA4 mutant molecule is L104EA29YIg.

REFERENCES:
patent: 4399216 (1983-08-01), Axel et al.
patent: 5434131 (1995-07-01), Linsley et al.
patent: 5521288 (1996-05-01), Linsley et al.
patent: 5580756 (1996-12-01), Linsley et al.
patent: 5637481 (1997-06-01), Ledbetter et al.
patent: 5770197 (1998-06-01), Linsley et al.
patent: 5773253 (1998-06-01), Linsley et al.
patent: 5844095 (1998-12-01), Linsley et al.
patent: 5851795 (1998-12-01), Linsley et al.
patent: 5883223 (1999-03-01), Gray
patent: 5885579 (1999-03-01), Linsley et al.
patent: 5885796 (1999-03-01), Linsley et al.
patent: 5916560 (1999-06-01), Larsen et al.
patent: 5958403 (1999-09-01), Strom et al.
patent: 5968510 (1999-10-01), Linsley et al.
patent: 5977318 (1999-11-01), Linsley et al.
patent: 5993800 (1999-11-01), Linsley et al.
patent: 6080412 (2000-06-01), Jordan et al.
patent: 6090914 (2000-07-01), Linsley et al.
patent: 6113898 (2000-09-01), Anderson et al.
patent: 6132992 (2000-10-01), Ledbetter et al.
patent: 6280957 (2001-08-01), Sayegh et al.
patent: 6352694 (2002-03-01), June et al.
patent: 6444792 (2002-09-01), Gray et al.
patent: 6534055 (2003-03-01), June et al.
patent: 6641809 (2003-11-01), Brady et al.
patent: 6685941 (2004-02-01), Thompson et al.
patent: 6719972 (2004-04-01), Gribben et al.
patent: 6750334 (2004-06-01), Gray et al.
patent: 6830937 (2004-12-01), Brady et al.
patent: 2001/0053361 (2001-12-01), Thompson et al.
patent: 2002/0031510 (2002-03-01), Larsen et al.
patent: 2002/0039577 (2002-04-01), Todderud et al.
patent: 2002/0115214 (2002-08-01), June et al.
patent: 2002/0182211 (2002-12-01), Peach et al.
patent: 2003/0007968 (2003-01-01), Adams et al.
patent: 2003/0083246 (2003-05-01), Cohen et al.
patent: 2003/0099622 (2003-05-01), Hering et al.
patent: 2003/0219863 (2003-11-01), Peach et al.
patent: 2004/0014171 (2004-01-01), Peach et al.
patent: 2004/0022787 (2004-02-01), Cohen et al.
patent: 2004/0047890 (2004-03-01), Weber et al.
patent: 2005/0214313 (2005-09-01), Peach et al.
patent: 0 613 944 (1994-09-01), None
patent: 0 682 039 (1995-11-01), None
patent: WO 90/05541 (1990-05-01), None
patent: WO 93/00431 (1993-01-01), None
patent: WO 93/19767 (1993-10-01), None
patent: WO94/01547 (1994-01-01), None
patent: WO 94/28912 (1994-12-01), None
patent: WO 94/29436 (1994-12-01), None
patent: WO95/06481 (1995-03-01), None
patent: WO95/28957 (1995-11-01), None
patent: WO02/02638 (1995-12-01), None
patent: WO95/33770 (1995-12-01), None
patent: WO 95/33823 (1995-12-01), None
patent: WO 95/34320 (1995-12-01), None
patent: WO 96/14865 (1996-05-01), None
patent: WO 96/23071 (1996-08-01), None
patent: WO 97/28267 (1997-08-01), None
patent: WO 98/31820 (1998-07-01), None
patent: WO 98/33513 (1998-08-01), None
patent: WO 98/56417 (1998-12-01), None
patent: WO99/39726 (1999-08-01), None
patent: WO99/39727 (1999-08-01), None
patent: WO 00/23115 (2000-04-01), None
patent: WO 01/54732 (2001-08-01), None
patent: WO 01/90122 (2001-11-01), None
patent: WO 01/92337 (2001-12-01), None
patent: WO02/083187 (2002-10-01), None
patent: WO 2004/058800 (2004-07-01), None
patent: WO 2004/058944 (2004-07-01), None
patent: WO 2005/016266 (2005-02-01), None
Merriam-Webster Online Dictionary: entry for “Regimen” (Mar. 8, 2005).
Shapiro et al., New England Journal of Medicine, 2000, 343: 230-238.
Komelli et al., 2000, J. Cell. Biol., 151: 863-878.
ElAntak et al., 2005, J. Biol. Chem., 280: 36802-36808.
Kuhnt et al., Enzyme Microb. Technol., 1997, 21 : 405-412 (reference provided by Applicant).
Abrams, Judith R. et al., “CTLA4lg-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris,”The Journal of Clinical Investigation, 1999, 103:1243-52 (Exhibit 13).
Azuma, Miyuki et al., “B70 antigen is a second ligand for CTLA-4 and CD28,”Nature, 1993, 366:76-9 (Exhibit 14).
Broach, James R., “Construction of High Copy Yeast Vectors Using 2-μm Circle Sequences,”Methods of Enzymology, 1983, 101:307-25 (Exhibit 15).
Byrn, Randal A. et al., “Characterization of In Vitro Inhibition of Human Immunodeficiency Virus by Purified Recombinant CD4,”Journal of Virology, 1989, 63:4370-5 (Exhibit 16).
Clarke, Louise et al., “Selection Procedure for Isolation of Centromere DNAs fromSaccharomyces cerevisiae,”Methods of Enzymology, 1983, 101:300-7 (Exhibit 17).
Cohen, Stanley N. et al., “Nonchromosomal Antibiotic Resistance in Bacteria: Genetic Transformation ofEscherichia coliby R-Factor DNA,”Proc. Natl. Acad. Sci. USA, 1972, 69:2110-4 (Exhibit 18).
Dash, Bret et al., “Deletion of a singleN-linked glycosylation site from the transmembrane envelope protein of human immunodeficiency virus type 1 stops cleavage and transport of gp160 preventingenv-mediated fusion,”Journal of General Virology, 1994, 75:1389-97 (Exhibit 19).
European Mycophenolate Mofetil Cooperative Study Group, “Placebo-controlled study of mycophenolate mofetil combined with cyclosporine and corticosteroids for prevention of acute rejection,”The Lancet, 1995, 345:1321-5 (Exhibit 20).
Falk, Kirsten et al., “Both Human and Mouse Cells Expressing H-2Kband Ovalbumin Process the Same Peptide, SIINFEKL,”Cellular Immunology, 1993, 150:447-52 (Exhibit 21).
Fiers, W. et al., “Complete nucleotide sequence of SV40 DNA,”Nature, 1978, 273:113-20 (Exhibit 22).
Freeman, Gordon J. et al., “B7, A New Member of the Ig Superfamily with Unique Expression on Activated and Neoplastic B Cells,”The Journal of Immunology, 1989, 143:2714-22 (Exhibit 23).
Freeman, Gordon J. et al., “Cloning of B7-2: A CTLA-4 Counter-Receptor that Costimulates Human T Cell Proliferation,”Science, 1993, 262:909-11 (Exhibit 24).
Fujikawa, Kiyomi et al., “Short Communications: Nuclear Localization and Transforming Activity of Human Papillomavirus Type 16 E7-β-Galactosidase Fusion Protein: Characterization of the Nuclear Localization Sequence,”Virology, 1994, 204:789-93 (Exhibit 25).
Gérard, C. et al., “Production and Characterization of Polyclonal Antibodies Recognizing the Intracytoplasmic Third Loop of the 5-Hyrdroxytryptamine1aReceptor,”Neuroscience, 1994, 62:721-39 (Exhibit 26).
Goeddel, David V. et al., “Synthesis of human fibroblast interferon byE. coli,”Nucleic Acids Research, 1980, 8:4057-74 (Exhibit 27).
Greene, JoAnne L. et al., “Covalent Dimerization of CD28/CTLA-4 and Oligomerization of CD80/CD86 Regulate T Cell Costimulatory Interactions,”Journal of Biological Chemistry, 1996, 271:26762-71 (Exhibit 28).
Hansen, John A. et al., “Monoclonal Antibodies Identifying a Novel T-Cell Antigen and Ia Antigens of Human Lymphocytes,”Immunogenetics, 1980, 10:247-60 (Exhibit 29).
Hess B. et al., “Cooperation of Glycolytic Enzymes,”Adv. Enzyme Reg., 1968, 7:149-67 (Exhibit 30).
Hitzeman, Ronald A. et al., “Isolation and Characterization of the Yeast 3-Phosphoglycerokinase Gene (PGK) by and Immunological Screening Technique,”The Journal of Biological Chemistry, 1980, 255:12073-80 (Exhibit 31).
Holland, Michael J. et al., “Isolation and Identification of Yeast Messenger Ribonucleic Acids Coding for Enolase, Glyceraldehyde-3-phosphate Dehydrogenase, and Phosphoglycerate Kinase,”Biochemistry, 1978, 17:4900-7 (Exhibit 32).
Ikeda, Toshio et al., “Isolation of a cDNA encoding the chicken p508/p97 (Lyt-10) transcription factor,”Gene, 1994, 138:193-6 (Exhibit 33).
Johnsson, Bo et al., “Immobilization of Proteins to a Carboxymethyldextran-Modified Gold Surface for Biospecific Interaction Analysis in Surface Plamon Resonance Sensors,”Analytical Biochemistry, 1991, 198:268-77 (Exhibit 34).
Jones, Nancy H. et al., “Isolation of com

Affiliated with

Also associated with

Rating

Methods for protecting allogeneic islet transplant using... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for protecting allogeneic islet transplant using..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for protecting allogeneic islet transplant using... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3860196