Methods for promoting functional regeneration of mammalian muscl

Details Methods for promoting functional regeneration of mammalian muscl Methods for promoting functional regeneration of mammalian muscl

1993-05-14

2000-07-25

Duffy, Patricia A.

Drug, bio-affecting and body treating compositions

Lymphokine

514 2, 514 12, A61K 4505

Patent

active

060933909

ABSTRACT:
The present invention relates to a method for regulating neuron development, maintenance and regeneration in the central and peripheral nervous systems of a mammal and to pharmaceutical compositions comprising leukaemia inhibitory factor with or without nerve growth factor useful for same. The present invention is particularly useful in the treatment of developmental and cerebral anomalies and neuropathies in mammals and in particular humans.

REFERENCES:
patent: 5166065 (1992-11-01), Williams et al.
patent: 5187077 (1993-02-01), Gearing et al.
Yuen et al, Annals Neurol, 40: 346-354, 1996.
Jackowski, A., British Journal of Neurosurgery 9: 303-317, 1995.
Varon et al. (1983/84) "Neuronotrophic and Neurite-Promoting Factors and their Clinical Potentials", Dev. Neurosci. 6, 73-100.
Fukada (1985) "Purification and Partial Characterization of a Cholingeric Neuronal Differentiation Factor", Proc. Natl. Acad. Sci. USA 82, 8795-8799.
Fingl et al. (1975) "The Pharmacological Basis of Therapeutics", Fifth Edition, MacMillan Publishing Co., Inc., 1-46.
Moreau et al. (1988) "Leukaemia Inhibitory Factor is Identical to the Myeloid Growth Factor Human Interleukin for DA Cells", Nature 336, 690-692. 1417.
Yamamori et al. (1989) "The Cholinergic Neuronal Differentiation Factor from Heart Cells is Identical to Leukemia Inhibitory Factor" Science 246, 1412-1416.
Gregoriadis et al (1993) Trends in Biotech. 11: 440-442.
Saneto et al (1987) "Neurochemistry", IRL Press, Ltd., Oxford, pp. 27-63.
Murphy et al (1991) Proc. Nat'l. Acad. Sci. 88: 3498-3501.
Kilpatrick et al (1991) J. Neurochem. 57 (Suppl.): 555.
Murphy et al (1991) J. Neurochem 57 (Suppl.): S16.

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