Methods for production of oligonucleotides

Details Methods for production of oligonucleotides Methods for production of oligonucleotides

2006-04-10

2011-12-20

Woolwine, Samuel (Department: 1637)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

C536S023100

Reexamination Certificate

active

08080393

ABSTRACT:
The present invention relates to production of oligonucleotides using rolling circle replication, wherein synthesised multimeric oligonucleotides are reduced to mononucleotides using a nicking cassette. Thus, the invention provides a method for the production of oligonucleotides, enabling efficient amplification of oligonucleotides at lengths up to at least 1000 nucleotides and in high amounts contained within a nicking cassette.

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