Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Reexamination Certificate
2008-01-29
2008-01-29
Le, Long V. (Department: 1641)
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
C435S041000, C435S084000, C435S101000, C435S252100, C435S441000, C435S444000, C514S054000
Reexamination Certificate
active
10353891
ABSTRACT:
Isolated strains of supercapsulatedstreptococciband at a density of no greater than 1.03 g/cm3in a Percoll gradient and are capable of producing hyaluronic acid with molecular weight exceeding 6 million Da. Methods of producing high molecular weight hyaluronic acid employ a supercapsulated strain ofstreptococcuswhich bands at a density of no greater than 1.03 g/cm3in a Percoll gradient. Methods of selectingstreptococcusstrains capable of producing hyaluronic acid with a molecular weight exceeding 6 million Da comprise, inter alia, cultivating supercapsulated strains ofstreptococciwhich band at a density of no greater than 1.03 g/cm3in a Percoll gradient.
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Pharmacia,Healon Sodium Hyaluronate,Product Information.
Wirt, H. et al.,New Aspects in the Surgical Treatment of Glaucomo Comparison of Viscoelastic Substances in Chamber Angle Surgery,BIOSIS No. 94126491.
Advanced Medical Optics Uppsala AB
Grun James L.
Le Long V.
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