Methods for production of astaxanthin from the green...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing a carotene nucleus

Reexamination Certificate

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C435S041000, C435S257300

Reexamination Certificate

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07063957

ABSTRACT:
A method for producing the high-value ketocarotenoid astaxanthin by the green microalgaChlorella zofingiensisin dark-heterotrophic cultures shows excellent growth and high-yield astaxanthin production on glucose-supplemented media in the dark. The specific growth rate and astaxanthin yield can be as high as 0.031 h−1, and 10.3 mg l−1, respectively, which are the highest so far reported in heterotrophic algal cultures. The light-independent astaxanthin-producing ability ofChlorella zofingiensiscan be employed for commercial production of astaxanthin using industrial fermenters.

REFERENCES:
patent: 3280502 (1966-10-01), Farrow et al.
Ip, P.-F., et al. 2004. Enhanced production of astaxanthin by the green microalgaChlorella zofingiensisin mixotrophic culture. Process Biochemistry 39: 1761-1766. Available online Nov. 4, 2003.

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