Methods for producing protein C

Details Methods for producing protein C Methods for producing protein C

1993-12-15

1997-04-08

Jacobson, Dian C.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435 23, 435 29, 435 691, 435375, C12N 510, C12N 516, C12Q 137, C12P 2100

Patent

active

056187149

ABSTRACT:
The present invention relates to a method for producing high levels of functional recombinant proteins in adenovirus-transformed mammalian cells by incubating cells capable of producing recombinant proteins at a temperature range between about 38 degrees centigrade and about 39 degrees centigrade. The method allows for higher levels of expression of total protein in some cell lines and higher levels of functional protein in other cell lines.

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