Methods for producing phospholipid metabolites in yeast

Details Methods for producing phospholipid metabolites in yeast Methods for producing phospholipid metabolites in yeast

1997-05-07

1999-06-01

Guzo, David

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 29, 435134, 435155, 435171, 435194, 4352541, 43525411, 4352542, 43525421, 435455, C12Q 102, C12Q 168, C12N 118

Patent

active

059087528

ABSTRACT:
Methods are provided for increased and controlled production of choline and inositol, choline and inositol metabolites, and choline- and inositol-containing phospholipids in yeast, comprising the step of increasing phosphatidylcholine (PC) turnover in yeast. Methods are also provided for detecting phospholipase D-mediated turnover of phosphatidylcholine in vivo in yeast, comprising an assay for choline excretion.

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