Methods for producing high affinity anti-human IgE-monoclonal an

Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses

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53038825, 43524027, 435 7021, C12N 1506, C12N 520, C07K 1642

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active

054222583

ABSTRACT:
Methods of producing monoclonal antibodies that bind to unique antigenic epitopes of IgE (designated ige.bl) which are present on IgE-bearing B cells but not basophils are described. The monoclonal antibodies block binding of IgE to mast cells and basophils in vitro.

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