Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2006-11-14
2006-11-14
Guzo, David (Department: 1636)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S320100, C435S235100, C435S455000, C435S325000
Reexamination Certificate
active
07135339
ABSTRACT:
The present invention provides novel pseudotyped retroviral vectors that can transduce human and other cells. Vectors are provided that are packaged efficiently in packaging cells and cell lines to generate high titer recombinant virus stocks expressing novel envelope glycoproteins. The present invention further relates to compositions for gene therapy.
REFERENCES:
patent: 5512421 (1996-04-01), Burns et al.
patent: 5643756 (1997-07-01), Kayman et al.
patent: 5654195 (1997-08-01), Sodroski et al.
patent: 5670354 (1997-09-01), Burns et al.
patent: 5693509 (1997-12-01), Cotten et al.
patent: 5711964 (1998-01-01), Dattagupta et al.
patent: 5739271 (1998-04-01), Sridhar et al.
patent: 6440730 (2002-08-01), Von Laer et al.
patent: 6531123 (2003-03-01), Chang
patent: 6555107 (2003-04-01), Poeschla et al.
patent: 6589763 (2003-07-01), Von Laer et al.
patent: 2003/0054548 (2003-03-01), Kaleko et al.
patent: 2005/0123517 (2005-06-01), McCray, Jr. et al.
patent: 1 006 196 (2000-06-01), None
patent: WO 98/44788 (1998-10-01), None
patent: WO 03/092582 (2003-11-01), None
GenBank Accession No. V00878 dated Feb. 25, 2003.
Altschul et al., “Gapped BLAST and PSI-BLAST: a new generation of protein database search programs,”Nucl. Acids. Res., 1997, 25 (17):3389-3402.
Altschul et al., “Basic Local Alignment Search Tool,”J. Mol. Biol., 1990, 215:403-410.
Alvarez-Buylla et al., “Identification of neural stem cells in the adult vertebrate brain,”Brain Res. Bull., 2002, 57(6):751-758.
Beyer et al., “Oncoretrovirus and Lentivirus Vectors Pseudotyped with Lymphocytic Choriomeningitis Virus Glycoprotein: Generation, Concentration, and Broad Host Range,”J. Virol., 2002, 76(3):1488-1495.
Beyer et al., “Recombinant Expression of Lymphocytic Choriomeningitis Virus Strain WE Glycoproteins: a Single Amino Acid Makes the Difference,”J. Virol., 2001, 75(2):1061-1064.
Boshart et al., “A Very Strong Enhancer Is Located Upstream of an Immediate Early Gene of Human Cytomegalovirus,”Cell, 1985, 41:521-530.
Buchmeier et al., “Arenaviridae: The Viruses and Their Replication,”Fields Virology, 4thed., 2001, Knipe and Howley (eds.), Lippincott Williams & Wilkins, vol. 2, pp. 1635-1668.
Burns et al., “Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: Concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells,”Proc. Natl. Acad. Sci. USA, 1993, 90:8033-8037.
Cao et al., “Identification of α-Dystroglycan as a Receptor for Lymphocytic Choriomeningitis Virus and Lassa Fever Virus,”Science, 1998, 282:2079-2081.
Chang et al., “ Human Immunodeficiency Viruses Containing Heterologous Enhancer/Promoters Are Replication Competent and Exhibit Different Lymphocyte Tropisms,”J. Virol., 1993, 67:743-752.
Chen et al., “Generation of packaging cell lines for pseudotyped retroviral vectors of the G protein of vesicular stomatitis virus by using a modified tetracycline inducible system,”Proc. Natl. Acad. Sci. USA, 1996, 93:10057-10062.
Corpet et al., “Multiple sequence alignment with hierarchical clustering,”Nucl. Acids. Res., 1988, 16:10881-10891.
Culyer et al., “Lymphocyte Gene Therapy,”Human Gene Ther., 1991, 2(2):107-109.
DePolo et al., “VSV-G Pseudotyped Lentiviral Vector Particles Produced in Human Cells Are Inactivated by Human Serum,”Mol. Ther., 2000, 2:218-222.
Dijkema et al., “Cloning and expression of the chromosomal immune interferon gene of the rat,”EMBO J., 1985, 4(3):761-767.
Doetsch et al., “Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult Mammalian Brain,”Cell, 1999, 97(6):703-716.
Doetsch et al., “Regeneration of a germinal layer in the adult mammalian brain,”Proc. Natl. Acad. Sci. USA, 1999, 96(20):11619-11624.
Duisit et al., “Five Recombinant Simian Immunodeficiency Virus Pseudotypes Lead to Exclusive Transduction of Retinal Pigmented Epithelium in Rat,”Mol. Ther., 2002, 6(4):446-454.
Gewirtz, “Oligodeoxynucleotide-Based Therapeutics for Human Leukemias,”Stem Cells, 1993, 11(Suppl. 3):96-103.
Goff, “Intracellular trafficking of retroviral genomes during the early phase of infection: viral exploitation of cellular pathways,”J. Gene Med., 2001, 3:517-528.
Gorman et al., “The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection,”Proc. Natl. Acad. Sci. USA, 1982, 79:6777-6781.
Grossman et al., “Successfulex vivogene therapy directed to liver in a patient with familiar hypercholesterolaemia,”Nat. Genet., 1994, 6:335-341.
Henry and Campbell, “A Role for Dystroglycan in Basement Membrane Assembly,”Cell, 1998, 95:859-870.
Henry and Campbell, “Dystroglycan inside and out,”Curr. Opin. Cell Biol., 1999, 11:602-607.
Higgins and Sharp, “Fast and sensitive multiple sequence alignments on a microcomputer,”CABIOS, 1989, 5(2):151-153.
Higgins et al., “CLUSTAL: a package for performing multiple sequence alignment on a microcomputer,”Gene, 1988, 73:237-244.
Huang et al., “Parallelization of a local similarity algorithm,”CABIOS, 1992, 8(2):155-165.
Johnston et al., “Minimum Requirements for Efficient Transduction of Dividing and Nondividing Cells by Feline Immunodeficiency Virus Vectors,”J. Virol., 1999, 73(6):4991-5000.
Kang et al., “In Vivo Gene Transfer Using a Nonprimate Lentiviral Vector Pseudotyped with Ross River Virus Glycoproteins,”J. Virol., 2002, 76(18):9378-9388.
Karlin and Altschul, “Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes,”Proc. Natl. Acad. Sci. USA, 1990, 87:2264-2268.
Karlin and Altschul, “Applications and statistics for multiple high-scoring segments in molecular sequences,”Proc. Natl. Acad. Sci. USA, 1993, 90:5873-5877.
Kasid et al., “Human gene transfer: Characterization of human tumor-infiltrating lymphocytes as vehicles for retroviral-mediated gene transfer in man,”Proc. Natl. Acad. Sci. USA, 1990, 87:473-477.
Kenyon et al., “Aerosol Infection of Rhesus Macaques with Junin Virus,”Intervirology, 1992, 33:23-31.
Kim et al., “Use of the human elongation factor 1α promoter as a versatile and efficient expression system,”Gene, 1990, 91:217-223.
Lehninger, “The amino acid building blocks of proteins,”biochemistry, 2ndedition, 1975, The Johns Hopkins University School of Medicine, pp. 73-75.
Lever, “HIV and other lentivirus-based vectors,”Gene Therapy, 1996, 3:470-471.
Maniatis et al., “Regulation of Inducible and Tissue-Specific Gene Expression,”Science, 1987, 236:1237-1245.
Mann et al., “Construction of a Retrovirus Packaging Mutant and Its Use to Produce Helper-Free Defective Retrovirus,”Cell, 1983, 33:153-159.
Markowitz et al., “A Safe Packaging Line for Gene Transfer: Separating Viral Genes on Two Different Plasmids,”J. Virol., 1988, 62(4):1120-1124.
Meinkoth and Wahl, “Hybridization of Nucleic Acids Immobilized on Solid Supports,”Anal. Biochem., 1984, 138:267-284.
Miletic et al., “Retroviral Vectors Pseudotyped with Lymphocytic Choriomeningitis Virus,”J. Virol., 1999, 73(7):6114-6116.
Miller, “Human gene therapy comes of age,”Nature, 1992, 357:455-460.
Miller, “Cell-surface receptors for retroviruses and implications for gene transfer,”Proc. Natl. Acad. Sci. USA, 1996, 93:11407-11413.
Mizushima and Nagata, “pEF-BOS, a powerful mammalian expression vector,”Nucl. Acids Res., 1990, 18(17):5322.
Myers and Miller, “Optimal alignments in linear space,”CABIOS, 1988, 4(1):11-17.
Neckers and Whitesell, “Antisense technology: biological utility and p
Davidson Beverly L.
McCray, Jr. Paul B.
Guzo David
University of Iowa Research Foundation
Viksnins Harris & Padys PLLP
LandOfFree
Methods for producing and using in vivo pseudotyped... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods for producing and using in vivo pseudotyped..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for producing and using in vivo pseudotyped... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3630759