Methods for producing amino substituted chromanes and...

Details Methods for producing amino substituted chromanes and... Methods for producing amino substituted chromanes and...

2005-02-15

2005-02-15

Solola, Taofiq (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C549S407000

Reexamination Certificate

active

06855833

ABSTRACT:
Disclosed are processes for producing chromane compounds, preferably chroman-2-yl acetic acid compounds and 6-amino-chroman-2-yl acetic acid esters which are intermediates for producing platelet aggregation inhibitors and/or are themselves potent platelet aggregation inhibitors.

REFERENCES:
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M. J. Fisher, et al., “Fused Bicyclic Gly-Asp β-Turn Mimics with Specific Affinity for GPIIb-IIIa,” Journal of Medicinal Chemistry, vol. 42, No. 23, 1999, pp. 4875-4889.
Wulff, et al., Über die Eignung Verschiedener Aldehyde und Ketone als Haftgruppen für Monoalkohole,Chem Ber., 119, 1876-1889 (1986), XP001037635.
Buehler, et al., “2-Hydroxy-5-Nitrobenzyl Chloride,” Org., Synth., vol. 20, 1940, pp. 59-61.
T. Inoue, et al., “A New Synthesis of o-Quinonemethides and Their Inter-and Intramolecular Cyclization Reactions,” Bull. Chem. Soc. Jpn, vol. 63, pp. 1062-1068 (1990).

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