Liquid purification or separation – Processes – Separating
Patent
1994-09-01
1996-04-30
Kim, John
Liquid purification or separation
Processes
Separating
210774, 422 40, 435 2, 604406, 604408, B01D 3700, B01D 3600
Patent
active
055121870
ABSTRACT:
A blood processing method provides a red blood cell product that is free of microorganisms like Yersinia enterocolitica during storage periods over 24 hours. The red blood cell product is collected in a first container, where it is refrigerating to cool the blood product to a temperature of about 3 to 5 degrees C. The refrigerated product is transferred from the first container into a storage container through a prescribed filter medium that comprises a mass of synthetic fibers having an average fiber diameter of about 10 microns or less and a bulk density of about 0.7 gram per cubic centimeter or less. The filtered product is retained in the storage container at a temperature of about 3 to 5 degrees C. for a storage period over 24 hours after filtration. Using the filter medium, microorganisms like Yersinia enterocolitica present in the red blood cell product at the time of collection are depleted. The filtered blood product remains free of clinically significant numbers of microorganisms throughout refrigerated storage up to time of transfusion.
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Buchholz Donald H.
Kandler Richard L.
Barrett Joseph B.
Baxter International Inc.
Kim John
Price Bradford R. L.
Ryan Daniel D.
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