Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...
Reexamination Certificate
2007-08-28
2007-08-28
Haddad, Maher M. (Department: 1644)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Amino acid sequence disclosed in whole or in part; or...
C514S008100
Reexamination Certificate
active
10296423
ABSTRACT:
The present invention provides a method for reducing stroke-related tissue damage by treating a mammal with E-selectin. Preferably, this treatment induces E-selectin tolerance in the mammal. Another aspect of the invention is a method for inducing E-selectin tolerance in a mammal through intranasal administration of E-selectin, preferably including booster administrations. The present methods are especially adapted for use in patients at increased risk of stroke or who may become at increased risk of stroke.
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Hallenbeck John M.
Spatz Maria
Takeda Hidetaka
Haddad Maher M.
Schwegman, Lundberg, Woessner and Kluth P.A.
United States of America as represented by the Secretary of the
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