Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2008-03-18
2008-03-18
Kim, Young J. (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
Reexamination Certificate
active
10861378
ABSTRACT:
Methods for preventing inhibition of nucleic acid synthesis by pyrophosphate are disclosed. More specifically, the present invention concerns inhibiting or preventing pyrophosphorolysis in sequencing and amplification of nucleic acid molecules. According to the present invention, an enzyme which is a pentosyltransferase, a phosphotransferase with an alcohol group as acceptor, a nucleotidyltransferase, or a carboxy-lyase is added to the reaction which serves to remove pyrophosphate from the reaction mixture.
REFERENCES:
patent: 4403035 (1983-09-01), Anderson et al.
patent: 4595660 (1986-06-01), Ostroff et al.
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4683202 (1987-07-01), Mullis
patent: 4766072 (1988-08-01), Jendrisak et al.
patent: 4767708 (1988-08-01), Minkley, Jr. et al.
patent: 4795699 (1989-01-01), Tabor et al.
patent: 4800159 (1989-01-01), Mullis et al.
patent: 4851331 (1989-07-01), Vary et al.
patent: 4863849 (1989-09-01), Melamede
patent: 4952496 (1990-08-01), Studier et al.
patent: 4962020 (1990-10-01), Tabor et al.
patent: 4965188 (1990-10-01), Mullis et al.
patent: 4971903 (1990-11-01), Hyman
patent: 5001050 (1991-03-01), Blanco et al.
patent: 5003059 (1991-03-01), Brennan
patent: 5026645 (1991-06-01), Kotani et al.
patent: 5047342 (1991-09-01), Chatterjee
patent: 5075216 (1991-12-01), Innis et al.
patent: 5079352 (1992-01-01), Gelfand et al.
patent: 5091310 (1992-02-01), Innis
patent: 5102802 (1992-04-01), McAllister
patent: 5106729 (1992-04-01), Lindsay et al.
patent: 5108892 (1992-04-01), Burke et al.
patent: 5122457 (1992-06-01), Reim et al.
patent: 5124247 (1992-06-01), Ansorge
patent: 5126251 (1992-06-01), Moss et al.
patent: 5142033 (1992-08-01), Innis
patent: 5173411 (1992-12-01), Tabor et al.
patent: 5192674 (1993-03-01), Oshima et al.
patent: 5198543 (1993-03-01), Blanco et al.
patent: 5210036 (1993-05-01), Comb et al.
patent: 5242818 (1993-09-01), Oshima et al.
patent: 5270179 (1993-12-01), Chatterjee
patent: 5308751 (1994-05-01), Ohkawa et al.
patent: 5322785 (1994-06-01), Comb et al.
patent: 5332666 (1994-07-01), Prober et al.
patent: 5352778 (1994-10-01), Comb et al.
patent: 5374553 (1994-12-01), Gelfand et al.
patent: 5403709 (1995-04-01), Agrawal et al.
patent: 5405746 (1995-04-01), Uhlen
patent: 5405747 (1995-04-01), Jett et al.
patent: 5405774 (1995-04-01), Abramson et al.
patent: 5405776 (1995-04-01), Kotewicz et al.
patent: 5407799 (1995-04-01), Studier
patent: 5409811 (1995-04-01), Tabor et al.
patent: 5411862 (1995-05-01), Ruggiu et al.
patent: 5413926 (1995-05-01), Oshima et al.
patent: 5420029 (1995-05-01), Gelfand et al.
patent: 5424190 (1995-06-01), Fuller
patent: 5432065 (1995-07-01), Fuller
patent: 5436149 (1995-07-01), Barnes
patent: 5436326 (1995-07-01), Ishino et al.
patent: 5455170 (1995-10-01), Abramson et al.
patent: 5466591 (1995-11-01), Abramson et al.
patent: 5474920 (1995-12-01), Moses
patent: 5480980 (1996-01-01), Seela
patent: 5484701 (1996-01-01), Cocuzza et al.
patent: 5489523 (1996-02-01), Mather
patent: 5498523 (1996-03-01), Tabor et al.
patent: 5500363 (1996-03-01), Comb et al.
patent: 5503980 (1996-04-01), Cantor
patent: 5512458 (1996-04-01), Leonard
patent: 5512462 (1996-04-01), Cheng
patent: 5516633 (1996-05-01), Fuller
patent: 5525464 (1996-06-01), Drmanac et al.
patent: 5525470 (1996-06-01), Cohen et al.
patent: 5545552 (1996-08-01), Mathur
patent: 5547859 (1996-08-01), Goodman et al.
patent: 5550035 (1996-08-01), Moss et al.
patent: 5665551 (1997-09-01), Gelfand et al.
patent: 6291164 (2001-09-01), Blakesley
patent: 6764839 (2004-07-01), Blakesley
patent: 1311201 (1992-12-01), None
patent: 0 386 858 (1990-09-01), None
patent: 0 386 859 (1990-09-01), None
patent: 0 409 078 (1991-01-01), None
patent: 0 482 714 (1992-04-01), None
patent: 0 547 359 (1993-06-01), None
patent: 0 647 716 (1995-04-01), None
patent: 0 701 000 (1996-03-01), None
patent: 0 712 927 (1996-05-01), None
patent: 0 763 599 (1997-03-01), None
patent: 7-163343 (1995-06-01), None
patent: 8-9999 (1996-01-01), None
patent: WO 90/10064 (1990-09-01), None
patent: WO 90/12111 (1990-10-01), None
patent: WO 91/09950 (1991-07-01), None
patent: WO 92/06188 (1992-04-01), None
patent: WO 92/06202 (1992-04-01), None
patent: WO 93/02212 (1993-02-01), None
patent: WO 93/04184 (1993-03-01), None
patent: WO 93/05060 (1993-03-01), None
patent: WO 93/06243 (1993-04-01), None
patent: WO 93/20232 (1993-10-01), None
patent: WO 93/23564 (1993-11-01), None
patent: WO 94/03643 (1994-02-01), None
patent: WO 94/05797 (1994-03-01), None
patent: WO 94/16107 (1994-07-01), None
patent: WO 94/26911 (1994-11-01), None
patent: WO 95/04162 (1995-02-01), None
patent: WO 95/14770 (1995-06-01), None
patent: WO 95/15380 (1995-06-01), None
patent: WO 95/20682 (1995-08-01), None
patent: WO 95/23236 (1995-08-01), None
patent: WO 95/27067 (1995-10-01), None
patent: WO 95/28636 (1995-10-01), None
patent: WO 96/10640 (1996-04-01), None
patent: WO 96/14405 (1996-05-01), None
patent: WO 96/14417 (1996-05-01), None
patent: WO 96/14434 (1996-05-01), None
Nyren, P, “Apyrase Immobilized on Paramagnetic Beads Used to Improve Detection limits in Bioluminometric ATP Monitoring,” Journal of Biochemiluminescence and Chemiluminescence, 1994, vol. 9, pp. 29-34.
Abbots, J., et al., “Studies on Mechanism ofEscherichia coliDNA Polymerase I Large Fragment,”J. Biol. Chem. 263:15094-15103 (1988).
Allen, T., et al., “Cloning and expression of the adenine phosphoribosyltransferase gene fromLeishmania donovani,” Molecular and Biochemical Parasitology 74:99-103 (Oct. 1995).
Beabealashvilli, R.S., et al., “Nucleoside 5′-triphosphates modified at sugar residues as substrates for calf thymus terminal deoxynucleotidyl transferase and for AMV reverse transcriptase,”Biochimica et Biophysica Acta 868(213):136-144 (1986).
Beato, M., “Gene Regulation by Steroid Hormones,”Cell 56:335-344 (1989).
Boisclair, Y.R., and Brown, A.L., “Use of Reverse Ligation-PCR to Identify Transcriptional Start Sites in GC-Rich TATA-Less Genes: Application to the Rat IGFBP-2 Gene,”DNA and Cell Biol. 14:731-739 (1995).
Brock, K.V., et al., “Nucleotide sequencing of 5′and 3′termini of bovine viral diarrhea virus by RNA ligation and PCR,”J. Virol. Meth. 38:39-46 (1992).
Brooks, R.R., and Anderson, J.A., “Substrate, Metal and Template Effects on Inhibition of Bacteriophage-Qβ Ribonucleic Acid Polymerase by Ortho- and Pyro- phosphate,”Biochem. J. 171:725-732 (1978).
Bult, C.J., et al., “Complete Genome Sequence of the Methanogenic Archaeon,Methanococcus jannaschii,” Science 273:1058-1072 (Aug. 1996).
Calhoun, D.H., et al., “Location of therhoGene and Characterization of λilv-galDerivatives of λilv-rhoBacteriophage,”Mol. Gen. Genet. 193:205-209 (1984).
Charng, Y., et al., “Molecular cloning and expression of the gene encoding ADP-glucose pyrophosphorylase from the cyanobacteriumAnabaenasp. strain PCC 7120,”Plant Mol. Biol. 20(1):37-47 (1992).
Chidgeavadze, Z.G., and Beabealashvilli, R.S., “2′, 3′-Dideoxy-3′aminonucleoside 5′triphosphates are the terminators of DNA synthesis catalyzed by DNA polymerases,”Nucl. Acids Res. 12(3):1671-1686 (1984).
Chidgeavadze, Z.G., et al., “3′-Floro-2′,3′-dideoxyribonucleoside 5′-triphosphates: terminators of DNA synthesis,”FEBS Letters 183:275-278 (1985).
Chidgeavadze, Z.G., et al., “Nucleoside 5′-triphosphates with modified sugars as substrates for DNA polymerases,”Biochimica et Biophysica Acta 868(213): 145-152 (1986).
Cunningham, P.R., and Ofengand, J., “Use of Inorganic Pyrophosphatase to Improve the Yield of In Vitro Transcription Reactions Catalyzed by T7 RNA Polymerase,”BioTechniques 9:713-714 (1990).
Deissler, H., et al., “Affinity Purification and cDNA Cloning of Rat Neural Differentiation and Tumor Cell Surface Antigen gp130RB13-6Reveals Relationship to Human and Murine PC-1,”J. Bio
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