Methods for preventing dental calculus in domestic animals

Drug – bio-affecting and body treating compositions – Dentifrices – Phosphate compound containing

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424401, 424439, 424440, 424441, 424442, 426805, 426807, 426 89, 426 92, 426 96, 426 97, 426 98, 426302, 426574, 426635, A61K 716, A61K 3342, A61K 4700

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052962172

ABSTRACT:
The novel agents for preventing dental calculus in domestic animals of the present invention are sequestering agents that are applied as coatings to commercially-prepared diets for domestic animals and that are significantly superior in terms of their anticalculus efficacy to the soluble pyrophosphate crystal growth inhibitors of the prior art. The sequestering agents of the present invention form soluble calcium complexes in saliva and dental plaque fluids thereby preventing the calcification of dental plaque. Sodium hexametaphosphate has been utilized as the preferred sequestering agents of the invention to date.

REFERENCES:
patent: 2191199 (1940-02-01), Hall
patent: 3004897 (1961-10-01), Shore
patent: 3475533 (1969-10-01), Mayrand
patent: 3620767 (1971-11-01), Swartz
patent: 4011346 (1977-03-01), Ernst
patent: 4044158 (1977-08-01), Burkwall, Jr.
patent: 4297382 (1981-10-01), Hosaka
patent: 4324811 (1982-04-01), Eugley
patent: 4357318 (1982-11-01), Shah et al.
patent: 4444800 (1984-04-01), Bixby et al.
patent: 4460565 (1984-07-01), Westrate et al.
patent: 4603054 (1986-07-01), Schmidt et al.
patent: 4627977 (1986-12-01), Gaffar et al.
patent: 4784862 (1988-11-01), Wotherspoon
patent: 4806342 (1989-02-01), Gaffar et al.
patent: 4808400 (1989-02-01), Gaffar et al.
patent: 4808401 (1989-02-01), Gaffar et al.
patent: 4913895 (1990-04-01), Miyake et al.
patent: 4915937 (1990-04-01), Amjad
patent: 4921692 (1990-05-01), Gaffar et al.
patent: 4921693 (1990-05-01), Gaffar et al.
patent: 5000940 (1991-03-01), Staples et al.
patent: 5000943 (1991-03-01), Scaglione et al.
patent: 5000944 (1991-03-01), Prencipe et al.
patent: 5000973 (1991-03-01), Scaglione et al.
patent: 5006361 (1991-04-01), Cox
patent: 5011679 (1991-04-01), Spanier et al.
patent: 5015485 (1991-05-01), Scaglione et al.
patent: 5017362 (1991-05-01), Gaffar et al.
patent: 5037637 (1991-08-01), Gaffar et al.
patent: 5043154 (1991-08-01), Gaffar et al.
patent: 5047231 (1991-09-01), Spanier et al.
patent: 5094870 (1992-03-01), Scaglione et al.
patent: 5114704 (1992-05-01), Spanier et al.
M. D. Francis and W. W. Briner, "Animal Calculus: Methods of Evaluation and of Dietary Production and Control," J. Dent. Res. 48, 1185-1195 (1969).
M. D. Francis, "The Inhibition of Calcium Hydroxyapatite Crystal Growth by Polyphosphonates and Polyphosphates," Calc. Tiss. Res. 3, 151-162 (1969).
F. J. Draus, M. Lesniewski and F. L. Miklos, "Pyrophosphate and Hexametaphosphate Effects in In Vitro Calculus Formation," Archs. Oral Biol. 15, 893-896 (1970).
W. W. Briner, M. D. Francis and J. S. Widder, "The Control of Dental Calculus in Experimental Animals," The International Dental Journal 21, 61-73 (1971).
G. P. Barnes, G. K. Stookey and J. C. Muhler, "In Vitro Studies of the Calculus-Inhibiting Properties of Tooth Surface Polishing Agents and Chelating Agents," J. Dent. Res. 50(4), 966-975 (1971).
M. D. Francis and W. W. Briner, "The Effect of Phosphonates on Dental Enamel In Vitro and Calculus Formation In Vivo," Calc. Tiss. Res. 11, 1-9 (1973).
W. W. Briner and M. D. Francis, "In Vitro and In Vivo Evaluation of Anti-Calculus Agents," Calc. Tiss. Res. 11, 10-22 (1973).
G. K. Stookey and J. L. McDonald, Jr., "Chemical Prevention of Calculus Formation in the Rat," J. Dent. Res. 53(6), 1334-1337 (1974).
D. J. White, W. D. Bowman, E. Cox, M. Best, C. A. Rodlun, J. M. Warrick and G. K. Stookey, "In Vitro and In Vivo Studies of Anticalculus Agents," J. Dent. Res. 68, Special Issue, Abstracts of Papers 1586, 380 (1989).
G. K. Stookey and J. M. Warrick, "Additivity of Antimicrobial Agents and Crystal Growth Inhibitors for Calculus Prevention in an Animal Model," Caries Research 24, Abstracts 6, 398 (1990).
F. J. Draus, W. J. Tarbet and F. L. Miklos, "Salivary Enzymes and Calculus Formation," J. Periodont. Res. 3, 232-235 (1968).

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