Methods for preparing synthetic repetitive DNA

Details Methods for preparing synthetic repetitive DNA Methods for preparing synthetic repetitive DNA

1996-09-03

1998-11-03

Degen, Nancy

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435 6, 435 691, 4352528, 4353201, 536 231, 536 241, 536 253, C12P 1934, C12P 2102, C07H 2104, C12Q 168

Patent

active

058307133

ABSTRACT:
Methods are provided for the production of large polypeptides containing repeating sequences of amino acids utilizing biochemical techniques, specifically DNA sequences coding for the expression of the large polypeptides. Systems utilizing exogenous transcriptional and translational regions to control the production of the large polypeptides are also provided.

REFERENCES:
patent: 5023171 (1991-06-01), Ho et al.
patent: 5089406 (1992-02-01), Williams et al.
patent: 5641648 (1997-06-01), Ferrari et al.
Wosnick et al., "Total Chemical Sysnthesis and Expression in Escherichia coli of a maize glutathione-transferase (GST) gene," Gene, 76:153-160 (1989).
Newton and Graham, "4. Klonierung von PCR Produkten," PCR, Spektrum Akademischer Verlag:Heidelberg, pp. 63-70 (1994).
White et al., "Concatemer Chain Reaction: A Taq DNA Polymerase-Mediated Mechanism for Generating Long Tandemly Repetitive DNA Sequences," Analytical Biochemistry, 199:184-190 (1991).
Rudert and Trucco, "DNA Polymers of Protein Binding Sequences Generated by PCR," Nucleic Acids Research, 18(21):6460 (1990).
Ijdo et al., "Improved Telomere Detection Using a Telomere Repeat Probe (TTAGGG).sub.n generated by PCR," Nucleic Acids Research, 19(17):4780 (1991).
Dougherty et al., "Biosynthesis of New Polymers of Controlled Molecular Structure," Makromol. Chem.; Macromol. Symp. 62:225-229 (1992).
Doel, M.T., et al., "The Expression in E. Coli of Synthetic Repeating Polymeric Genes Coding for Poly(L-Aspartyl-L-Phenylalanine)," Nucleic Acids Research, 8(20):4575-4592 (1980).
White, T.J., et al., "The Polymerase Chain Reaction," Trends in Genetics, 5(6):(Jun. 1989).
Kempe, T., et al., "Multiple-Copy Genes: Production and Modification of Monomerica Peptides from Large Multimeric Fusion Proteins," Gene, 39:239-245 (1985).
Kangas, T.T., et al., "Expression of a Proline-Enriched Protein in Escherichia coli," 43(3):629-635 (1982).
White et al Trends in Genetics 5(6) 185-189, 1989.
Doel et al Nucleic Acids Research 8 4575-4592, 1980.
Hein et al Nucleosides & Nucleotides 7 497-510, 1988.
Cserpan et al Acta Chemica Scandinavica 45 265-272, 1991.
McClain et al. Nucleic Acids Research 14 6670, 1986.
Kempe et al. Gene 39 239-245, 1985.

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