Methods for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo-[1,2-A]pyrr

Details Methods for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo-[1,2-A]pyrr Methods for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo-[1,2-A]pyrr

1996-02-21

1997-04-15

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548530, 548543, C07D48704, C07D20712, C07D20716

Patent

active

056211155

ABSTRACT:
This invention pertains to methods for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo-[1,2-a]pyrrole-1-carboxylic acids represented by formula (I): ##STR1## In a first embodiment, the method comprises the sequential steps of cyclizing, via a free radical ring closure reaction, and hydrolyzing a compound represented by formula (IV): ##STR2## wherein R.sub.1 is lower alkyl. In a second embodiment, the method comprises the sequential steps of hydrolyzing and decarboxylating a compound represented by formula (VIII): ##STR3##

REFERENCES:
patent: 4087539 (1978-05-01), Muchowski et al.
patent: 4089969 (1978-05-01), Muchowski et al.
patent: 4097579 (1978-06-01), Muchowski et al.
patent: 4140698 (1979-02-01), Van Horn et al.
patent: 4344943 (1982-08-01), Muchowski
patent: 4347185 (1982-08-01), Muchowski et al.
patent: 4347186 (1982-08-01), Muchowski et al.
patent: 4347187 (1982-08-01), Muchowski et al.
patent: 4353829 (1982-10-01), Thurber et al.
patent: 4456759 (1984-06-01), Muchowski et al.
patent: 4458081 (1984-07-01), Muchowski et al.
patent: 4496741 (1985-01-01), Doherty
patent: 4505927 (1985-03-01), Muchowski et al.
patent: 4835288 (1989-05-01), Khatri et al.
patent: 4849526 (1989-07-01), Fleming et al.
patent: 4873340 (1989-10-01), Muchowski et al.
patent: 4874871 (1989-10-01), Fleming et al.
patent: 4988822 (1991-01-01), Muchowski et al.
patent: 5082950 (1992-01-01), Muchowski et al.
patent: 5082951 (1992-01-01), Muchowski et al.

Affiliated with

Also associated with

Rating

Methods for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo-[1,2-A]pyrr does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo-[1,2-A]pyrr, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo-[1,2-A]pyrr will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-361971