Methods for preparation and use of psorospermin analogs

Details Methods for preparation and use of psorospermin analogs Methods for preparation and use of psorospermin analogs

2007-07-17

2007-07-17

McKenzie, Thomas (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C549S391000, C549S392000

Reexamination Certificate

active

10152152

ABSTRACT:
Psorospermin is a cytotoxic dihydroflranoxanthone that has found to exhibit significant activity against various tumor cell lines. Unfortunately, psorospermin is no longer readily available from its natural plant source. The present invention is directed to a method for preparing psorospermin and psorospermin analogs. Methods are also disclosed for utilizing psorospermin analogs to inhibit cellular proliferation.

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