Methods for predicting the behaviour of breast tumours

Details Methods for predicting the behaviour of breast tumours Methods for predicting the behaviour of breast tumours

1994-09-22

1997-12-02

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 912, 435 71, 435 72, 435 79, 435 691, 536 231, 536 243, 536 2433, 5303881, 530300, 530350, C12Q 168, C12P 1934, C07K 1528, C07K 1300

Patent

active

056934653

ABSTRACT:
The estrogen-regulated gene sequence pLIV1 has been discovered and isolated, and found to be significantly associated with the metastatic spread of breast cancer cells to the regional lymph nodes. Methods are therefore provided for determining the risk of metastasis of a female breast tumour, as well as for predicting the responsiveness to endocrine treatment of a female breast tumour, which involve determining whether a tissue sample from a tumour expresses a polypeptide containing the pLIV1 gene sequence, or a substantial portion thereof.

REFERENCES:
Gura, Science 270:575-577, 1995.
James, Antiviral Chemistry and Chemotherapy 2:191-214.
Guiterrez, The Lancet 339:715-721, 1992.
Talmadge, Adv. Drug Delivery Reviews 10:247-299, 1993.
Sigma Catalog, 1992.
Freeman et al., Advanced Drug Delivery Reviews 12: 169-183, 1993.

Affiliated with

Also associated with

Rating

Methods for predicting the behaviour of breast tumours does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for predicting the behaviour of breast tumours, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for predicting the behaviour of breast tumours will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-800144