Drug – bio-affecting and body treating compositions – Extract or material containing or obtained from an alga as...
Reexamination Certificate
2005-12-20
2005-12-20
Naff, David M. (Department: 1651)
Drug, bio-affecting and body treating compositions
Extract or material containing or obtained from an alga as...
C424S093700, C424S257100, C424S274100, C424S276100, C424S439000, C435S257300, C435S946000
Reexamination Certificate
active
06977076
ABSTRACT:
Chlorellaextracts containing high molecular weightChlorellapolysaccharide and polysaccharide complexes show immune modulatory, specifically immune stimulatory, activity. The polysaccharide and polysaccharide complexes contain glucose and any combination of: galactose, rhamnose, mannose and arabinose, as well as N-acetyl glucosamine and N-acetyl galactosamine. The extracts may be treated with pronase, DNAse, RNAse and proteases to remove unassociated nucleic acids, ribonucleic acids and proteins. The extracts may also undergo treatment to effect cleavage of specific glycosidic linkages, the linkages being defined by their susceptibility to cleavage by amylase, amyloglucosidase, cellulase or neuraminidase.Chlorellaextracts may be administered to a mammal to increase proliferation of splenocytes and increase production of cytokines such as IL-6, IL-10, INF-γ and TNF-α. They may be used as a supplement to a vaccination regimen.
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Naff David M.
Ocean Nutrition Canada Limited
Ware Deborah K.
LandOfFree
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