Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1995-05-26
1998-03-17
Feisee, Lila
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 9, 514 11, A61K 3805
Patent
active
057286809
ABSTRACT:
This invention provides methods for normalizing the numbers of lymphocytes in animals by administering the dipeptide L-Glu-L-Trp.
REFERENCES:
patent: 3679787 (1972-07-01), Bergy et al.
patent: 4002602 (1977-01-01), Goldstein
patent: 4010148 (1977-03-01), Goldstein
patent: 4077949 (1978-03-01), Goldstein
patent: 4079127 (1978-03-01), Goldstein et al.
patent: 4116951 (1978-09-01), Wang
patent: 4120951 (1978-10-01), Goldstein
patent: 4133804 (1979-01-01), Bach et al.
patent: 4148788 (1979-04-01), Wang
patent: 4167557 (1979-09-01), Goldstein
patent: 4261886 (1981-04-01), Goldstein et al.
patent: 4264571 (1981-04-01), Goldstein et al.
patent: 4297276 (1981-10-01), Goldstein et al.
patent: 4339427 (1982-07-01), Goldstein et al.
patent: 4353821 (1982-10-01), Birr et al.
patent: 4374828 (1983-02-01), Folkers et al.
patent: 4377511 (1983-03-01), Lopukhin et al.
patent: 4388234 (1983-06-01), Horecker
patent: 4389343 (1983-06-01), Horecker
patent: 4395404 (1983-07-01), Low et al.
patent: 4396605 (1983-08-01), Birr
patent: 4426324 (1984-01-01), Meienhofer
patent: 4427783 (1984-01-01), Newman et al.
patent: 4428938 (1984-01-01), Kisfaludy et al.
patent: 4442031 (1984-04-01), Felix et al.
patent: 4466918 (1984-08-01), Birr et al.
patent: 4470926 (1984-09-01), Birr et al.
patent: 4500450 (1985-02-01), Seipke et al.
patent: 4504415 (1985-03-01), Felix et al.
patent: 4505853 (1985-03-01), Goldstein et al.
patent: 4517119 (1985-05-01), Felix et al.
patent: 4526717 (1985-07-01), Seipke et al.
patent: 4571336 (1986-02-01), Houck et al.
patent: 4579840 (1986-04-01), Hahn
patent: 4599231 (1986-07-01), Milich et al.
patent: 4612365 (1986-09-01), Birr et al.
patent: 4614731 (1986-09-01), Horecker
patent: 4621135 (1986-11-01), Trainin et al.
patent: 4634682 (1987-01-01), Erickson et al.
patent: 4659694 (1987-04-01), Horecker
patent: 4696915 (1987-09-01), Horecker
patent: 4699898 (1987-10-01), Gottlieb
patent: 4711952 (1987-12-01), Kasafirek et al.
patent: 4722999 (1988-02-01), Handschumacher et al.
patent: 4751216 (1988-06-01), Gottlieb
patent: 4752602 (1988-06-01), Lipsky et al.
patent: 4814434 (1989-03-01), Goldfarb
patent: 4826680 (1989-05-01), Jaeger
patent: 4904643 (1990-02-01), Brunetti et al.
patent: 4910296 (1990-03-01), Birr et al.
patent: 4946945 (1990-08-01), Wojdani
patent: 4983387 (1991-01-01), Goldstein et al.
patent: 5070076 (1991-12-01), Morozov et al.
patent: 5538951 (1996-07-01), Morozov et al.
patent: 5569585 (1996-10-01), Goodwin et al.
Rodionov et al, Vestn. Dermoatol. Venerol, 1:42-43, 1990.
Stites & Terr, Basic & Clinical Immunology, Prentice Hall, Norwalk, 1991, pp. 272-281.
Brostoss et al, Clinical Immunol, Gower Med. Pub. London, 1991, p. 30.10.
van der Zeijst et al, J. Exp. Med, 1978, 147:1253-1266.
Anisimov et al. (1982) Mechanisms of Ageing and Development, 19:245-258.
Anisimov et al. (1989) Mechanisms of Ageing and Development, 49:245-247.
Demidov et al. (1991) "Effects of Thymus Preparations and Antituberculous Drugs on Immunological Reactivity and the Course of Tuberculous Process in Experimental Animals", Probl. Tuberk., 12;52-54 (Chemical Abstracts 116 (17), Abstract No. 165824Y).
Goldstein et al. (1972) Proc. Natl. Acad. Sci. USA, 69:1800-1803.
Grigoriants et al. (1991) "Immunocorrection in the Combined Treatment of Patients with Osteomyelities Developing Following Combined Injuries to the Maxillofacial and Craniocerebral Areas", Stomatologiia (Mosk), 5:53-54 (Medline Abstract No. 92188368).
Iakovlev et al. (1991) "The Biochemical And Immunological Indices in the Rehabilitation Period of the Victims of the Accident on The Komsomolets Atomic Submarine", Voen. Med. ZH, 9:28-33 (Medline Abstract No. 92101433).
Khmel'nitskii et al. (1991) "Morphofunctional Characteristics of the Immunocompetent System in Hypotrophy and Its Correction By Thymogen", Arkh. Patol. 53:24-27 (Medline Abstract No. 92171772).
Low et al. (1981) Proceedings of the National Academy of Science, 78:1162-1166.
Rodionov et al., (1991) "Natural Killer Activity in Patients with Chronic Dermatoses", Vestn. Dermatol. Venerol. 5:4-6, (Biological Abstract vol. 92, Abstract No. 100385).
Rodionov et al. (1990) "The Immunocorrective Therapy of Pyoderma Caused by Staphylococci Multiply Resistant to Antibiotics", Vestn. Dermatol. Venerol., 1:42-45 (Medline Abstract No. 90224329).
Werner, G. H. et al. (1986) "Immunomodulating peptides," Experientia, 42:521-531.
Aliev, M.G. et al., "Simulation of thymus dysfunction in guinea pigs by using immunomodulators" Chem. Abstracts 116:664 Abstract No. 171986u (1992).
ASM News 56:368 (1990).
Belokrylov, G. et al., "Ability of some amino acids incorporated into protein to stimulate the thymus-dependent immune response" Eksp. Biol. Medit. 102:51-53 (1986).
Bespalov, V.G. et al., "Inhibiting effect of thymogen, a synthetic analog of thymalin, on the development of esophagus and forestomach tumors induced by N-nitrososarcosine ethyl ester in rats" Chem. Abstracts 111:23 Abstract No. 146389r (1989).
Gee, N.S. and Kenny, A.J., "Proteins of the kidney microvillar membranes" Biochem. J. 246:97-102 (1987).
Jaroff, L. "Stop that Germ|" Time, pp. 55-64 (May 23, 1988).
Pettit, G.R., in: Synthetic Peptides, vol. 3, Academic Press, NY, pp. 130, 134, 143, 424, 427, 429, and 434 (1975).
Remington's Pharmaceutical Sciences, Mack Publishing Co., Easton, PA, pp. 996-997, 1465-1469, 1553-1557 (1980).
Sandstrom, E.G. and Kaplan, J.C., "Antiviral therapy in AIDS: Clinical pharmacological properties and therapeutic experience to date" Drugs 34:372-390 (1987).
Sievertsson, H. et al., "Synthesis of Di-and tripeptides and assay in Vivo for activity in the thyrotrol releasing hormone and the luteinizing releasing hormone systems" J. Med. Chem. 15(1):8-11 (1971).
Khavinson Vladimir Kh.
Morozov Vyacheslav G.
Cytoven J.V.
Feisee Lila
Ungar Susan
LandOfFree
Methods for normalizing numbers of lymphocytes does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods for normalizing numbers of lymphocytes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for normalizing numbers of lymphocytes will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-957667