Methods for monitoring the expression of alternatively...

Details Methods for monitoring the expression of alternatively... Methods for monitoring the expression of alternatively...

2006-08-08

2006-08-08

Martinell, James (Department: 1634)

Data processing: measuring, calibrating, or testing

Measurement system in a specific environment

Biological or biochemical

C702S019000, C435S006120

Reexamination Certificate

active

07089121

ABSTRACT:
Methods, probe arrays and computer software products are provided for determining the arrangement of sequence elements. In one embodiment, methods for making and using exon chips are provided. The exon chips may be used to identify and quantify splice variants.

REFERENCES:
Gelfand et al (Proc. Natl. Acad. Sci. USA 93: 9061 (1996)).
Mironov et al (Genomics 51: 332 (1998)).
Flores et al (Genome Res. 8: 967 (1998)).
Wang et al., “Gene Structure-Based Splice Variant Deconvolution Using a Microarray Platform”, Bioinformatics (2003) vol. 18 Suppl. 1: 1315-1322.
Li and Wong, “Model-Based Analysis of Oligonucleolide Arrays: Expression Index Computation and Outlier Detection”, Proc. Natl. Acad. Sci. (2001) vol. 98 No. 1: 31-36.
Hu et al., “Predicting Splice Variant from DNA Chip Expression Data”, Genome Research (2001) 11: 1237-1245.

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