Methods for monitoring multiple gene expression

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C435S254100, C536S023100

Reexamination Certificate

active

07387875

ABSTRACT:
The present invention relates to methods for monitoring differential expression of a plurality of genes in a first filamentous fungal cell relative to expression of the same genes in one or more second filamentous fungal cells using microarrays containingTrichoderma reeseiESTs or SSH clones, or a combination thereof. The present invention also relates to computer readable media and substrates containing such array features for monitoring expression of a plurality of genes in filamentous fungal cells.

REFERENCES:
patent: WO 0049177 (2000-08-01), None
patent: WO 00/56762 (2000-09-01), None
Schmoll et al. Cloning of genes expressed early during cellulase induction inHypocrea jecorinaby a rapid subtraction hybridization approach Fungal Genetics and Biology 41:877-887, 2004.
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Foreman et al., Transcriptional Regulation of Biomass-degrading Enzymes in the Filamentous FungusTrichoderma reesei, The Journal of Biological Chemistry, 2003, vol. 278, No. 34, pp. 31988-31997.
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