Methods for minimizing thioamide impurities

Details Methods for minimizing thioamide impurities Methods for minimizing thioamide impurities

2008-01-01

2008-01-01

Wilson, James O. (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

C544S054000, C548S411000, C548S453000, C548S455000, C548S543000, C548S544000, C548S556000

Reexamination Certificate

active

07314932

ABSTRACT:
Methods for minimizing the formation of thioamide compounds using decoy agents during reactions, such as thionations of carbonyl compounds containing nitrite groups, are provided.

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Zhang et al., “Novel 6-aryl-1,4-dihydrobenzo[1,3]oxazine-2-thiones as Potent, Selective and Orally Active Nonsteroidal Progesterone Receptor Agonists”, Bioorg. Med. Chem. Lett. 13:1313-1316 (Apr. 7, 2003).

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