Methods for making lysophosphatidylcholine

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435128, 435131, 435198, 514724, C12P 1300, C12P 900, C12P 764

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active

057168148

ABSTRACT:
Methods for making lysophosphatidylcholine are provided, comprising hydrolysis of a mixture of phosphatidylcholine and an agent with phospholipase A.sub.2. Also disclosed are methods for making a lipid matrix of lysophosphatidylcholine, monoglyceride and fatty acid.

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Hughes, A., The Action of Snake Venoms on Surface Films, Biochem, J. 29:437-444 (1935).
Hanahan, D.J., The Enzymatic Degradation of Phosphatidyl Choline in Diethyl Ether; J. Biol. Chem. 195:199-206 (1952).
Dawson, R.M.C., On the Mechanism of Action of Phospholipase A. Biochem, J. 88:414-423 (1963).
Lecitase, Product Sheet, Novo Nordisk (1990).
Small, D.M., A Classification of Biologic Lipids Based Upon Their Interaction in Aqueous Systems, The Journal of the American Oil Chemist's Society, vol. 45, pp. 108-119 (1968).

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