Methods for making intermediates and oxytocin analogues

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 6 to 7 amino acid residues in defined sequence

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C530S315000, C530S317000, C530S330000, C530S333000

Reexamination Certificate

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07816489

ABSTRACT:
More efficient and/or economical methods for synthesizing heptapeptide alcohol analogs of oxytocin are provided along with novel intermediates which are useful in synthesizing such oxytocin analogs. Efficient and economical methods for synthesizing intermediates useful in synthesizing these oxytocin analogs are also provided.

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Kawai et al, “Poly-L-Homocysteine”, Polymer Journal (1976), vol. 8, No. 2, pp. 158-166.
Prochazka et al., “Analongs of Deamino Carba Oxytocin With Inhibitory Properties; Synthesis and Biological Activities”, Collection of Czechoslovak Chemical Communications (1992), vol. 57, pp. 1335-1344.

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