Methods for introducing heterologous cells into fish

Details Methods for introducing heterologous cells into fish Methods for introducing heterologous cells into fish

2006-12-21

2010-11-23

Bertoglio, Valarie (Department: 1632)

Multicellular living organisms and unmodified parts thereof and

Method of using a transgenic nonhuman animal in an in vivo...

C800S020000, C424S009200, C424S009100, C424S009600, C435S004000, C435S007100, C435S007230

Reexamination Certificate

active

07838726

ABSTRACT:
The invention provides methods of introducing heterologous cells into fish. After introduction cells remain viable, and in some instances proliferate, for sufficient time to conduct a variety of analyses on the heterologous cells or the fish or both. Such methods are useful for screening potential drugs for toxicity toward introduced cells or for capacity to stimulate differentiation and/or proliferation of introduced cells. Such methods are also useful for diagnosing the presence of small quantities of cancerous cells or pathogens in patient tissue samples. Such methods are also useful for culturing cells for subsequent use in cell or tissue engineering.

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