Methods for inhibiting B lymphocyte proliferation with...

Details Methods for inhibiting B lymphocyte proliferation with... Methods for inhibiting B lymphocyte proliferation with...

2000-07-27

2010-11-16

Zeman, Robert A (Department: 1645)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

C424S144100, C530S350000, C530S388200

Reexamination Certificate

active

07833529

ABSTRACT:
Soluble, secreted tumor necrosis factor receptor polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed. The polypeptides comprise one cysteine-rich repeat that is homologous to other tumor necrosis factor receptors, such as transmembrane activator and CAML-interactor (TACI). The polypeptides may be used for detecting ligands, agonists and antagonists. The polypeptides may also be used in methods that modulate B cell activation.

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