Methods for inhibiting activity of polyamine transporters

Details Methods for inhibiting activity of polyamine transporters Methods for inhibiting activity of polyamine transporters

2005-05-13

2008-09-16

Kumar, Shailendra (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

C514S646000

Reexamination Certificate

active

07425579

ABSTRACT:
A method for inhibiting the activity of a natural polyamine transporter comprising the step of contacting the transporter with an inhibitorily effective amount of a compound of formula (I) or (II):wherein L is a linker; R1=H, methyl, ethyl or propyl; R2=H or methyl; 0<x<3; 0<y<3; 2<v<5; and 2<w<8. Such a method is particularly useful for treating disorders involving the control of polyamine transport.

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