Methods for increasing yields of recombinant proteins

Details Methods for increasing yields of recombinant proteins Methods for increasing yields of recombinant proteins

1997-05-12

1999-06-22

Wax, Robert A.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

530412, 530419, 530422, 530350, 435 691, C07K 100, C07K 1400, C12N 1500

Patent

active

059143908

ABSTRACT:
Methods are disclosed for increasing the yields of recombinant proteins. Addition of one or more protective agents, such as a sulfated compound (including heparin, heparin sulfate, sodium dodecyl sulfate, and the like), hyaluronic acid or deoxycholate, to recombinant protein production processes is disclosed. Addition of protective agents to the recombinant production process results in increased yields of recombinant proteins.

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