Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Reexamination Certificate
2007-02-20
2007-02-20
Jones, Dameron L. (Department: 1618)
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
C424S009100, C424S009300, C424S009320, C534S007000
Reexamination Certificate
active
10356240
ABSTRACT:
In certain embodiments, methods of the present invention obtain dynamic data sets of an NMR spectroscopy signal of polarized129Xe in a selected structure, environment, or system. The signal data can be used to evaluate: (a) the physiology of a membrane or tissue; (b) the operational condition or function of a body system or portion thereof (when at rest or under stimulation); and/or (c) the efficacy of a therapeutic treatment used to treat a diagnosed disorder, disease, or condition. Thus, the present invention provides methods for screening and/or diagnosing a respiratory, cardiopulmonary disorder or disease such as chronic heart failure, and/or methods for monitoring the efficacy of therapeutics administered to subject to treat the disorder or disease.
REFERENCES:
patent: 6491895 (2002-12-01), Driehuys et al.
patent: 6808699 (2004-10-01), Driehuys et al.
patent: 03/024324 (2003-03-01), None
Mansson, Sven, et.al., “Characterization of diffusing capacity and perfusion of the rat lung in a lipopolysaccaride disease model using hyperpolarized 129Xe” Magnetic Resonance in Medicine: Official Journal of the society of Magnetic Resonance in Medicine/Society of Magnetic Resonance in Medicine. Dec. 2003, vol. 50, No. 6, pp. 1170-1179.
International Search Report and Written Opinion for PCT/US2004/002782 dated Jun. 25, 2004 with amendment thereto dated Jul. 16, 2004.
Swanson, et.al. “Distribution and Dyamics of Laser-Polarized 129Xe Magnetization Invivo” Mag. Rs. Med., vol. 42, pp.1137-1145 (1999).
Driehuys Bastiaan
Hall Margaret
Mansson Sven
Marelli Claudio
Wolber Jan
Chisholm Robert F.
Jones Dameron L.
Medi--Physics, Inc.
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