Methods for in vivo delivery of substantially water insoluble ph

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules

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424465, 424489, A61K 948

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active

054396867

ABSTRACT:
In accordance with the present invention, there are provided compositions for the in vivo delivery of substantially water insoluble pharmacologically active agents (such as the anticancer drug taxol) in which the pharmacologically active agent is delivered in a soluble form or in the form of suspended particles. In particular, the soluble form may comprise a solution of pharmacologically active agent in a biocompatible dispersing agent contained within a protein walled shell. Alternatively, the protein walled shell may contain particles of taxol. In another aspect, the suspended form comprises particles of pharmacologically active agent in a biocompatible aqueous liquid.

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