Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2006-10-13
2011-12-13
Horlick, Kenneth R. (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S091200
Reexamination Certificate
active
08076082
ABSTRACT:
Methods for simultaneously surveying the status of a large number of DNA mutation markers are described. In addition, methods for simultaneously determining the methylation status at multiple sites of a collection of genes, in a single assay, are described.
REFERENCES:
patent: 5834181 (1998-11-01), Shuber
patent: 2003/0119005 (2003-06-01), Brush et al.
patent: 2003/0143584 (2003-07-01), Li-Sucholeiki
patent: 2005/0227265 (2005-10-01), Barany et al.
patent: WO 03/006677 (2003-01-01), None
patent: WO 2004/081191 (2004-09-01), None
Sun, X. et al., “Detection of Tumor Mutations in the Presence of Excess Amounts of Normal DNA” Nature Biotechnology, vol. 19, pp. 186-189, Feb. 2002.
International Search Report for International Application No. PCT/US2006/040357, Sep. 2007.
Jeffreys, Alec J. et al.: “DNA Enrichment by Allele-Specific Hybridization (DEASH): A Novel Method for Haplotyping and for Detecting Low-Frequency Base Substitutional Variants and Recombinant DNA Molecules.” Genome Research, vol. 13, No. 10. Oct. 2003, pp. 2316-2324, XP-002553628 ISSN: 1088-9051.
Sun, Xiyuan et al.: “Detection of Mononucleotide Repeat Sequence Alterations in a Large Background of Normal DNA for Screening High-Frequency Microsatellite Instability Cancers.” Clinical Cancer Research, The American Association for Cancer Research, US, vol. 12, No. 2, Jan. 15, 2006, pp. 454-459, XP-002429105 ISSN: 1078-0432.
Supplementary European Search Report for Application No. EP 06 81 6985, Dec. 2009.
Cleveland State University
Fay Sharpe LLP
Horlick Kenneth R.
Tung Joyce
LandOfFree
Methods for identifying multiple DNA alteration markers in a... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods for identifying multiple DNA alteration markers in a..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for identifying multiple DNA alteration markers in a... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4307251