Methods for identifying inhibitors of neuronal degeneration

Details Methods for identifying inhibitors of neuronal degeneration Methods for identifying inhibitors of neuronal degeneration

2005-12-27

2005-12-27

Ulm, John (Department: 1646)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S007100, C435S455000

Reexamination Certificate

active

06979537

ABSTRACT:
The present invention concerns methods and means for identifying inhibitors of neuronal degeneration, and their use in the treatment of neurodegenerative disorders. In particular the invention concerns methods and means for identifying inhibitors of neuronal degeneration or cell death by taking advantage of the involvement of presenilin (PS) and Par-4 in NF-κB activation.

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