Methods for identifying human cell lines useful for...

Details Methods for identifying human cell lines useful for... Methods for identifying human cell lines useful for...

2007-05-08

2007-05-08

Ketter, James (Department: 1636)

Chemistry: molecular biology and microbiology

Vector, per se

C435S463000

Reexamination Certificate

active

10351397

ABSTRACT:
The invention concerns human cells which, due to an activation of the endogenous human EPO gene, are able to produce EPO in an adequate quantity and purity to enable a cost-effective production of human EPO as a pharmaceutical preparation. Furthermore the invention concerns a process for the production of such human EPO-producing cells, DNA constructs for the activation of the endogenous EPO gene in human cells as well as a process for the large-scale production of EPO in human cells.

REFERENCES:
patent: 4806524 (1989-02-01), Kawaguchi et al.
patent: 4992419 (1991-02-01), Woog et al.
patent: 6391633 (2002-05-01), Stern et al.
patent: 6565844 (2003-05-01), Treco et al.
patent: 2003/0148465 (2003-08-01), Chan et al.
patent: WO 96/19573 (1996-06-01), None

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