Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing
Patent
1995-05-17
2000-11-28
Duffy, Patricia A.
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
435 71, 435 792, G01N 3353
Patent
active
061531715
ABSTRACT:
Methods for identifying compounds that can be used for treatment of neurodegenerative diseases, for monitoring the progression of these diseases, and for monitoring therapeutic intervention of these diseases are provided. These methods are effected by determining the relative amount of .alpha.-sAPP and the ratio of .alpha.-sAPP to total sAPP in body fluids, tissues or in cell culture.
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Rowe Blake Alan
Siegel Robert Steven
Wagner Steven Lee
Duffy Patricia A.
Seidman Stephanie L.
SIBIA Neurosciences Inc.
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