Methods for identifying binding partners, agonists, and antagoni

Details Methods for identifying binding partners, agonists, and antagoni Methods for identifying binding partners, agonists, and antagoni

1997-04-14

1999-11-02

Kemmerer, Elizabeth

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

435 4, 435194, C12Q 148, C12Q 100

Patent

active

059768932

ABSTRACT:
A serine/theonine kinase protein which is associated with mitotic and meiotic cell division and which is characterized by having a kinase domain in its N-terminus and three PEST regions in the C-terminus, and nucleic acid molecules encoding the protein. Diagnostic and therapeutic methods using the serine/threonine kinase protein and nucleic acid molecules are also described.

REFERENCES:
patent: 5451518 (1995-09-01), Kolesnick
Llamazares, S. et al., Genes & Dev. 5:2153-2165, 1991.
Kitada, K. et al., Mol. and Cell. Biol. 13(7):4445-4457, 1993.
Fenton, B. & Glover, D. M., Nature 363:637-640, 1993.
Sharon, G. & Simchen, G., Genet. 125:475-485, 1990.
Schild, D. & Byers, B., Genet. 96:859-876, 1980.
Simmons, D. L. et al., Mol. and Cell. Biol. 12(9):4164-4169, 1992.
Clay, F. J. et al., Proc. Natl. Acad. Sci. USA 90:4882-4886, 1993.
van den Heuvel, S. and Harlow E., Science 262:2050-2054, 1993.
Dennis, J. W. (1986) Cancer Res. 46:4594-4600.
Heffernan, M. & Dennis, J. W. (1991) Nucleic Acids Research 19(1):85-92.
Padgett, R. A., et al., Ann. Rev. Biochem. 55, 1119-1150, 1986.
Kozak, M. (1986) Cell 44:283-292.
Shaw, G. & Kamen, R. (1986) Cell 46:659-667.
Hanks, S. K. & Quinn, A. M. (1991) Methods. Enzymol. 200:38-63.
Rogers, S., Wells, R. & Rechsteiner, M. (1986) Science 234:364-368.
Stein, R., Mori, N., Matthews, K., Lo, L. C. & Anderson, D. J. (1988) Neuron 1, 463-476.
Hamanaka et al., Cell Growth Diff. 5:249-257, Mar. 1994.
Kruger et al., J. Neuroscience, 11(8):2303, Aug. 1991.
Golsteyn et al., J. Cell Sci., 107:1509-1577, Jun., 1994.

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