Methods for identification of modulatory compounds for the expre

Details Methods for identification of modulatory compounds for the expre Methods for identification of modulatory compounds for the expre

1996-04-05

1998-12-01

Wax, Robert A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving hydrolase

435212, 435219, 435226, F41G 326

Patent

active

058436944

ABSTRACT:
The expression and purification of normal epithelial specific polypeptide (NES 1) which is expressed in normal cells, but not in radiation transformed cells, are described. Both the DNA sequence encoding the NES1 and the corresponding amino acid sequence are disclosed. Also, disclosed are methods for carcinoma detection and treatment using the NES1 as well as methods of identifying compounds modulating the expression and activity of NES1.

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