Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2011-04-05
2011-04-05
Steele, Amber D. (Department: 1639)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S004000, C530S350000, C506S009000
Reexamination Certificate
active
07919259
ABSTRACT:
The present invention relates to in vivo and in vitro methods, agents and compound screening assays for inhibiting extra-cellular matrix degradation, including joint degenerative inhibiting and/or anti-inflammatory pharmaceutical compositions, and the use thereof in treating and/or preventing a disease involving extra-cellular matrix degradation in a subject.
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Lin et al., 1994, Effect of manganese on tyrosylprotein sulfotransferase activity in PC12 cells, Biochemical Pharmacology, 47(9): 1575-1580.
Nakamura et al., “Isolation and Expression Profiling of Genes Upregulated in Bone Marrow-Derived Mononuclear Cells of Rheumatoid Arthritis Patients,” DNA Research 13, pp. 169-183 (2006).
Brys Reginald
Tomme Peter Herwig Maria
Vandeghinste Nick
Galapagos N.V.
Savitzky Martin
Steele Amber D.
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