Methods for genetic modification of hematopoietic progenitor...

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Reexamination Certificate

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C435S006120, C435S091100, C435S091310, C435S320100, C435S455000, C435S458000, C536S023100, C536S024500

Reexamination Certificate

active

10192980

ABSTRACT:
Described are compositions and methods relating to gene therapy, particularly as applied to hematopoietic progenitor (HP) cells, to transduced cells and methods of obtaining them, and to methods of using them to provide prolonged engraftment of modified hematopoietic cells in human subjects. The invention particularly relates to ex vivo gene therapy of HP cells for treatment or prevention of HIV infection.

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